[CAS NO. 61038-31-1] 10-Formyl-5,8-dideazafolicacid
PRODUCTS SPECIFICATIONS [61038-31-1]
DESCRIPTION [61038-31-1]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 467.43 |
| Molecular Formula | C22H21N5O7 |
| SMILES | O=C1C2=CC(CN(C3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(O)=O)=O)C=O)=CC=C2NC(N)=N1 |
Summary
10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor [1] .
IC50 & Target
thymidylate synthase [1]
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 50 mg/mL ( 106.97 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.1394 mL | 10.6968 mL | 21.3936 mL |
| 5 mM | 0.4279 mL | 2.1394 mL | 4.2787 mL |
| 10 mM | 0.2139 mL | 1.0697 mL | 2.1394 mL |
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1.
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2.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 1.25 mg/mL (2.67 mM); Clear solution