[CAS NO. 617-04-9] Methyl α-D-mannopyranoside

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PRODUCTS SPECIFICATIONS [617-04-9]

Catalog

HY-W039897

Brand

MCE

CAS

617-04-9

DESCRIPTION [617-04-9]

Overview

MDL	MFCD00063262
Molecular Weight	194.18
Molecular Formula	C7H14O6
SMILES	O[C@@H]1[C@@H](OC)O[C@H](CO)[C@@H](O)[C@@H]1O

For research use only. We do not sell to patients.

Summary

Methyl α-D-mannopyranoside could target macrophages in anti-tuberculosis inhalation therapy ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 514.99 mM ; Need ultrasonic)

H ₂ O : ≥ 100 mg/mL ( 514.99 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.1499 mL	25.7493 mL	51.4986 mL
5 mM	1.0300 mL	5.1499 mL	10.2997 mL
10 mM	0.5150 mL	2.5749 mL	5.1499 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (12.87 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (12.87 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (12.87 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Maretti E, et, al. Surface engineering of Solid Lipid Nanoparticle assemblies by methyl α-d-mannopyranoside for the active targeting to macrophages in anti-tuberculosis inhalation therapy. Int J Pharm. 2017 Aug 7; 528(1-2):440-451.

Synonyms

α-D-Mannopyranoside, methyl

Mannopyranoside, methyl, α-D-

Methyl α-D-mannopyranoside

1-O-Methyl-α-D-mannopyranoside

1-O-Methyl-α-mannopyranoside

Methyl α-D-mannoside

α-Methyl D-(-)-mannoside

NSC 1225