[CAS NO. 621-72-7] Bendazol

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PRODUCTS SPECIFICATIONS [621-72-7]

Catalog

HY-B2141

Brand

MCE

CAS

621-72-7

DESCRIPTION [621-72-7]

Overview

MDL	MFCD00022680
Molecular Weight	208.26
Molecular Formula	C14H12N2
SMILES	C1(CC2=CC=CC=C2)=NC3=CC=CC=C3N1

For research use only. We do not sell to patients.

Summary

Bendazol is a hypotensive drug which can also enhance NO synthase activity in renal glomeruli and collecting tubules.

IC50 & Target

NO synthase ^[1]

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 480.17 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.8017 mL	24.0085 mL	48.0169 mL
5 mM	0.9603 mL	4.8017 mL	9.6034 mL
10 mM	0.4802 mL	2.4008 mL	4.8017 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (12.00 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Eliseeva EV, et al. Effect of Hypotensive Drugs on Dynamics of Nitroxide-Producing Renal Function in Rats with Nephrogenic Hypertension. Bull Exp Biol Med. 2017 Jan;162(3):357-361.

Synonyms

1H-Benzimidazole, 2-(phenylmethyl)-

Benzimidazole, 2-benzyl-

2-(Phenylmethyl)-1H-benzimidazole

Bendazol

2-Benzylbenzimidazole

Dibasol

Dibazol

Dibazole

Tromasedan

Bendazole

NSC 60020

NSC 631632

2-Benzyl-1H-benzimidazole

2-Benzyl-1H-benzo[d]imidazole

2-Benzyl-1H-1,3-benzodiazole

2-Benzyl-1H-benzoimidazole