[CAS NO. 66-71-7] o-Phenanthroline
PRODUCTS SPECIFICATIONS [66-71-7]
DESCRIPTION [66-71-7]
Overview
| MDL | MFCD00011678 |
|---|---|
| Molecular Weight | 180.21 |
| Molecular Formula | C12H8N2 |
| SMILES | C12=C(N=CC=C3)C3=CC=C1C=CC=N2 |
Summary
o-Phenanthroline (1,10-Phenanthroline), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline (1,10-Phenanthroline) forms a red chelate with Fe 2+ that absorbs maximally at 510 nm. o-Phenanthroline (1,10-Phenanthroline) is also a MMP inhibitor [1] [2] .
In Vitro
o-Phenanthroline (1,10-Phenanthroline, 1mM) inhibits autolysis of sea cucumber body wall [2] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL ( 554.91 mM ; Need ultrasonic)
Ethanol : 50 mg/mL ( 277.45 mM ; Need ultrasonic)
H 2 O : 2 mg/mL ( 11.10 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 5.5491 mL | 27.7454 mL | 55.4908 mL |
| 5 mM | 1.1098 mL | 5.5491 mL | 11.0982 mL |
| 10 mM | 0.5549 mL | 2.7745 mL | 5.5491 mL |
References
- [1] Guan NanMu, et al. Synergistic inhibition between o-phenanthroline and chloride ion on cold rolled steel corrosion in phosphoric acid. Materials Chemistry and Physics Volume 86, Issue 1, 15 July 2004, Pages 59-68.
- [2] Zi-Qiang Liu, et al. The role of matrix metalloprotease (MMP) to the autolysis of sea cucumber (Stichopus japonicus). J Sci Food Agric. 2019 Oct;99(13):5752-5759.
Synonyms