[CAS NO. 67-47-0]  5-Hydroxymethylfurfural

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PRODUCTS SPECIFICATIONS [67-47-0]

Catalog
HY-Y0051
Brand
MCE
CAS
67-47-0

DESCRIPTION [67-47-0]

Overview

MDLMFCD00003234
Molecular Weight126.11
Molecular FormulaC6H6O3
SMILESO=CC1=CC=C(CO)O1

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE


Summary

5-Hydroxymethylfurfural (2-Hydroxymethyl-5-furfural), derived from Cornus officinalis , inhibits yeast growth and fermentation as stressors.


IC50 & Target

Yeast [1] .


In Vitro

It is found that furfural and HMF cause the attenuation of bulk translation activity and the assembly of cytoplasmic mRNP granules in Saccharomyces cerevisiae. Notably, a combination of furfural and HMF induce the remarkable repression of translation initiation and SG formation. Furfural and HMF can induce the formation of cytoplasmic mRNP granules, HMF also causes a gradual reduction in the polysome fraction and a concomitant increase in the 80S monosome fraction [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

<30°C Solid,>34°C Liquid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 50 mg/mL ( 396.48 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.9296 mL 39.6479 mL 79.2959 mL
5 mM 1.5859 mL 7.9296 mL 15.8592 mL
10 mM 0.7930 mL 3.9648 mL 7.9296 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (19.82 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (19.82 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (19.82 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

2-Furancarboxaldehyde, 5-(hydroxymethyl)-
2-Furaldehyde, 5-(hydroxymethyl)-
5-(Hydroxymethyl)-2-furancarboxaldehyde
HMF
5-Hydroxymethyl-2-formylfuran
5-Hydroxymethylfuraldehyde
5-(Hydroxymethyl)-2-furaldehyde
5-(Hydroxymethyl)-2-furancarbonal
5-(Hydroxymethyl)-2-furfural
5-(Hydroxymethyl)furfural
5-Oxymethylfurfurole
5-(Hydroxymethyl)-2-furfuraldehyde
5-Hydroxymethylfuran-2-aldehyde
Hydroxymethylfurfuraldehyde
5-Hydroxymethylfurfuraldehyde
2-Hydroxymethyl-5-furfural
Hydroxymethylfurfuralaldehyde
Hydroxymethylfurfural
NSC 40738
5-Hydroxymethylfurfurol
2-Formyl-5-hydroxymethylfuran
5-(Hydroxymethyl)furancarboxaldehyde
Aes 103
Hydroxymethylfuraldehyde
BAX 555
5-Hmf