[CAS NO. 672926-32-8] Kif15-IN-1
PRODUCTS SPECIFICATIONS [672926-32-8]
DESCRIPTION [672926-32-8]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 430.48 |
| Molecular Formula | C20H22N4O5S |
| SMILES | O=C(C1=CC=CC=C1N2)N([C@@H](C(C)C)C(NC3=NC(C)=C(C(OCC)=O)S3)=O)C2=O |
1 Publications Citing Use of MCE
Summary
Kif15-IN-1 is an inhibitor of the mitotic Kinesin family member 15 (Kif15) , and is used for the research of cellular proliferative diseases.
IC50 & Target
|
KIF15 |
In Vitro
Kif15-IN-1 (Compound 10) is an inhibitor of the mitotic kinesin Hs Kif15, with the potential activities against cellular proliferative diseases such as cancer, hyperplasias, restenosis, cardiac hypertrophy, immune disorders and inflammation [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : ≥ 100 mg/mL ( 232.30 mM )
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.3230 mL | 11.6149 mL | 23.2299 mL |
| 5 mM | 0.4646 mL | 2.3230 mL | 4.6460 mL |
| 10 mM | 0.2323 mL | 1.1615 mL | 2.3230 mL |
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1.
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2.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.5 mg/mL (5.81 mM); Clear solution