[CAS NO. 68729-05-5] ARM1

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PRODUCTS SPECIFICATIONS [68729-05-5]

Catalog

HY-W027340

Brand

MCE

CAS

68729-05-5

For research use only. We do not sell to patients.

ARM1 (4BSA) is a potent aminopeptidase and epoxide hydrolase inhibitor. ARM1 shows aminopeptidase inhibitory activity with an IC ₅₀ 7.61 µM and epoxide hydrolase inhibitory activity with an IC ₅₀ 12.4 µM ^[1] .

NCT Number	Sponsor	Condition	Start Date	Phase
NCT02356978	Assistance Publique - Hôpitaux de Paris	Crigler Najjar Syndrome\|Children	December 2014	Not Applicable
NCT03966131	Hospices Civils de Lyon	Toothless	September 2019	Not Applicable
NCT01813994	Yonsei University	Early Gastric Cancer or Gastric Adenoma	November 2014	Not Applicable
NCT02854202	Hospital de Clinicas Caracas\|Tel Aviv University	Type 2 Diabetes	August 2012	Not Applicable
NCT02748707	Tata Memorial Hospital	Oral Squamous Cell Carcinoma\|Carcinoma of Buccal Mucosa\|Tongue Cancers\|Head and Neck Cancers	August 18, 2015	Phase 2
NCT04187105	University of Illinois at Chicago	Acute Leukemia\|MDS	January 27, 2020	Phase 2
NCT04798638	TYK Medicines, Inc	Healthy Volunteers	April 30, 2021	Phase 1
NCT00202735	Sorlandet Hospital HF\|Oslo University Hospital\|Haukeland University Hospital\|Sykehuset i Vestfold HF\|Helse Stavanger HF\|Sykehuset Telemark\|Sykehuset Buskerud HF\|Blefjell Hospital HF\|Sykehuset Asker og Baerum\|St. Olavs Hospital\|University Hospital, Akershus	Shoulder Dislocation	January 2005	Phase 2\|Phase 3
NCT04428086	Jiangsu HengRui Medicine Co., Ltd.	Solid Tumor, Adult	July 27, 2020	Phase 1
NCT03331575	Shanghai Chest Hospital	Unresectable Stage III Non-small-cell Lung Cancer	November 2017	Phase 3
NCT03185988	Shen Lin\|Peking University	Targeted Therapy\|HER2\|Biliary Tract Cancer\|Esophageal Squamous Cell Carcinoma\|Colorectal Cancer	July 1, 2017	Phase 2

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 250 mg/mL ( 938.58 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: 2.08 mg/mL (7.81 mM); Suspended solution; Need ultrasonic

* All of the co-solvents are available by MCE.