[CAS NO. 6991-10-2] Swertisin

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PRODUCTS SPECIFICATIONS [6991-10-2]

Catalog

HY-N2189

Brand

MCE

CAS

6991-10-2

DESCRIPTION [6991-10-2]

Overview

MDL	-
Molecular Weight	446.40
Molecular Formula	C22H22O10
SMILES	O=C1C=C(C2=CC=C(O)C=C2)OC3=CC(OC)=C([C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)C(O)=C13

For research use only. We do not sell to patients.

Summary

Swertisin, a C-glucosylflavone isolated from Iris tectorum , is known to have antidiabetic, anti-inflammatory and antioxidant effects. Swertisin is an adenosine A1 receptor antagonist ^[1] ^[2] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL ( 112.01 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2401 mL	11.2007 mL	22.4014 mL
5 mM	0.4480 mL	2.2401 mL	4.4803 mL
10 mM	0.2240 mL	1.1201 mL	2.2401 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 1.25 mg/mL (2.80 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 1.25 mg/mL (2.80 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 1.25 mg/mL (2.80 mM); Clear solution

* All of the co-solvents are available by MCE.

Synonyms

4H-1-Benzopyran-4-one, 6-β-D-glucopyranosyl-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-

Swertisin

6-β-D-Glucopyranosyl-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one

Flavocommelitin

6-β-D-Glucopyranosyl-4′,5-dihydroxy-7-methoxyflavone

7-O-Methylapigenin 6-C-β-D-glucopyranoside

NSC 641547

Genkwanin 6-C-glucoside