[CAS NO. 71441-28-6] TTNPB
PRODUCTS SPECIFICATIONS [71441-28-6]
DESCRIPTION [71441-28-6]
Overview
| MDL | MFCD00673917 |
|---|---|
| Molecular Weight | 348.48 |
| Molecular Formula | C24H28O2 |
| SMILES | O=C(O)C1=CC=C(/C=C(C2=CC=C3C(C)(C)CCC(C)(C)C3=C2)\C)C=C1 |
3 Publications Citing Use of MCE
Summary
TTNPB (Ro 13-7410) (GMP) is TTNPB (HY-15682) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. TTNPB is a highly potent retinoic acid receptor (RAR) agonist [1] [2] .
In Vitro
The combination of TTNPB (Ro 13-7410) (GMP) (100 nM) and Laduviglusib (HY-10182) can induce chondrogenic markers in hiPSCs [2] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
The combination of TTNPB (Ro 13-7410) (GMP) (100 nM) and Laduviglusib (HY-10182) can form hyaline cartilaginous tissues in vivo [2] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
References
- [1] Pignatello MA, et al. Multiple factors contribute to the toxicity of the aromatic retinoid, TTNPB (Ro 13-7410): binding affinities and disposition. Toxicol Appl Pharmacol. 1997 Feb;142(2):319-27.
- [2] Manabu Kawata, et al. Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds. Stem Cell Reports. 2019 Sep 10;13(3):530-544.
Synonyms