[CAS NO. 73536-69-3] Bifendate

Ships within

Stock

Price

Qty

Total

$0.00

Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis

request a quote

If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [73536-69-3]

Catalog

HY-W018791

Brand

MCE

CAS

73536-69-3

DESCRIPTION [73536-69-3]

Overview

MDL	MFCD01751431
Molecular Weight	418.35
Molecular Formula	C20H18O10
SMILES	C2=C(OC)C1=C(OCO1)C(=C2C(OC)=O)C3=C(C=C(OC)C4=C3OCO4)C(OC)=O

For research use only. We do not sell to patients.

Summary

Bifendate (DDB) is a synthetic intermediate of Schisandrin C with anti- HBV efficacy in research of chronic hepatitis B ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL ( 119.52 mM ; Need ultrasonic)

H ₂ O : 1 mg/mL ( 2.39 mM ; ultrasonic and warming and heat to 80°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.3903 mL	11.9517 mL	23.9034 mL
5 mM	0.4781 mL	2.3903 mL	4.7807 mL
10 mM	0.2390 mL	1.1952 mL	2.3903 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (5.98 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (5.98 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Cui S, et al. [Anti-HBV efficacy of bifendate in treatment of chronic hepatitis B, a primary study]. Zhonghua Yi Xue Za Zhi. 2002 Apr 25;82(8):538-40.

Synonyms

[4,4′-Bi-1,3-benzodioxole]-5,5′-dicarboxylic acid, 7,7′-dimethoxy-, 5,5′-dimethyl ester

[4,4′-Bi-1,3-benzodioxole]-5,5′-dicarboxylic acid, 7,7′-dimethoxy-, dimethyl ester

Bifendate

DDB

Dimethyl 4,4′-dimethoxy-5,6,5′,6′-di(methylenedioxy)biphenyl-2,2′-dicarboxylate

DDB (pharmaceutical)

α-DDB

Dimethyl dicarboxylate biphenyl

Diphenyl dimethyl bicarboxylate

Bifendatatum