[CAS NO. 7681-67-6] Propionylpromazine hydrochloride
PRODUCTS SPECIFICATIONS [7681-67-6]
DESCRIPTION [7681-67-6]
Overview
| MDL | MFCD01941563 |
|---|---|
| Molecular Weight | 376.94 |
| Molecular Formula | C20H25ClN2OS |
| SMILES | CCC(C(C=C1N2CCCN(C)C)=CC=C1SC3=C2C=CC=C3)=O.[H]Cl |
Summary
Propionylpromazine hydrochloride (Propiopromazine hydrochloride), a dopamine receptor D2 ( DRD2 ) antagonist, can be used in the research of Parkinson disease [1] .
IC50 & Target
|
D 2 Receptor |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 83.33 mg/mL ( 221.07 mM ; Need ultrasonic)
H 2 O : 8.33 mg/mL ( 22.10 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.6529 mL | 13.2647 mL | 26.5294 mL |
| 5 mM | 0.5306 mL | 2.6529 mL | 5.3059 mL |
| 10 mM | 0.2653 mL | 1.3265 mL | 2.6529 mL |
-
1.
Add each solvent one by one: PBS
Solubility: 50 mg/mL (132.65 mM); Clear solution; Need ultrasonic
-
2.
-
3.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.08 mg/mL (5.52 mM); Clear solution