[CAS NO. 816-66-0]  4-Methyl-2-oxopentanoic acid

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PRODUCTS SPECIFICATIONS [816-66-0]

Catalog
HY-W012722
Brand
MCE
CAS
816-66-0

DESCRIPTION [816-66-0]

Overview

MDLMFCD00066204
Molecular Weight130.14
Molecular FormulaC6H10O3
SMILESCC(C)CC(C(O)=O)=O

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE


Summary

4-Methyl-2-oxopentanoic acid (α-Ketoisocaproic acid), an abnormal metabolite, is both a neurotoxin and a metabotoxin.


IC50 & Target

Human Endogenous Metabolite


Appearance

Liquid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 768.40 mM ; Need ultrasonic)

H 2 O : 100 mg/mL ( 768.40 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.6840 mL 38.4202 mL 76.8403 mL
5 mM 1.5368 mL 7.6840 mL 15.3681 mL
10 mM 0.7684 mL 3.8420 mL 7.6840 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: PBS

    Solubility: 100 mg/mL (768.40 mM); Clear solution; Need ultrasonic

  • 2.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (19.21 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (19.21 mM); Clear solution

  • 4.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (19.21 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

Pentanoic acid, 4-methyl-2-oxo-
Valeric acid, 4-methyl-2-oxo-
4-Methyl-2-oxopentanoic acid
α-Ketoisocaproic acid
α-Oxoisocaproic acid
2-Oxoisocaproic acid
2-Oxoleucine
2-Oxo-4-methylvaleric acid
2-Ketoisocaproic acid
2-Oxo-4-methylpentanoic acid
4-Methyl-2-oxovaleric acid
4-Methyl-2-oxopentanoate
Ketoleucine
α-Ketoisocapronic acid
2-keto-4-Methylvaleric acid
Isobutylglyoxylic acid
Ketoisocaproic acid