[CAS NO. 83-30-7] 2,4,6-Trihydroxybenzoic acid

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PRODUCTS SPECIFICATIONS [83-30-7]

Catalog

HY-W077292

Brand

MCE

CAS

83-30-7

DESCRIPTION [83-30-7]

Overview

MDL	MFCD00002453
Molecular Weight	170.12
Molecular Formula	C7H6O5
SMILES	O=C(O)C1=C(O)C=C(O)C=C1O

For research use only. We do not sell to patients.

Summary

2,4,6-Trihydroxybenzoic acid, the flavonoid metabolite, is a CDK inhibitor. 2,4,6-Trihydroxybenzoic acid can be used for the research of cancer ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 587.82 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.8782 mL	29.3910 mL	58.7820 mL
5 mM	1.1756 mL	5.8782 mL	11.7564 mL
10 mM	0.5878 mL	2.9391 mL	5.8782 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (14.70 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (14.70 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (14.70 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Sankaranarayanan R, et, al. The Flavonoid Metabolite 2,4,6-Trihydroxybenzoic Acid Is a CDK Inhibitor and an Anti-Proliferative Agent: A Potential Role in Cancer Prevention. Cancers (Basel). 2019 Mar 26;11(3):427.