[CAS NO. 84709-25-1] (-)-Zuonin A
PRODUCTS SPECIFICATIONS [84709-25-1]
DESCRIPTION [84709-25-1]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 340.37 |
| Molecular Formula | C20H20O5 |
| SMILES | C[C@H]1[C@@H](C)[C@@H](C2=CC=C(OCO3)C3=C2)O[C@@H]1C4=CC=C(OCO5)C5=C4 |
1 Publications Citing Use of MCE
Summary
IC50 & Target
|
JNK1 1.7 μM (IC 50 ) |
JNK2 2.9 μM (IC 50 ) |
JNK3 1.74 μM (IC 50 ) |
In Vitro
(−)-zuonin A binds the D-recruitment site (DRS) of JNK, a recruitment site utilized by substrates and other substrates to dock onto and recognize MAPKs
[1]
.
(−)-zuonin A inhibits the activation and phosphorylation of JNK by MKK4 and MKK7
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL ( 293.80 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.9380 mL | 14.6899 mL | 29.3798 mL |
| 5 mM | 0.5876 mL | 2.9380 mL | 5.8760 mL |
| 10 mM | 0.2938 mL | 1.4690 mL | 2.9380 mL |