[CAS NO. 85-68-7] Benzyl butyl phthalate
PRODUCTS SPECIFICATIONS [85-68-7]
DESCRIPTION [85-68-7]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 312.36 |
| Molecular Formula | C19H20O4 |
| SMILES | O=C(C1=CC=CC=C1C(OCC2=CC=CC=C2)=O)OCCCC |
1 Publications Citing Use of MCE
Summary
Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs) [1] [2] [3] .
In Vitro
Benzyl butyl phthalate (BBP) is commonly added during the manufacturing of plastics to increase flexibility and elasticity
[1]
.
Benzyl butyl phthalate induces histone modifications in
S1PR3
in side population (SP) cells, but not in non-SP cells
[3]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Liquid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Pure form | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
H 2 O : 100 mg/mL ( 320.14 mM ; Need ultrasonic)
DMSO : 100 mg/mL ( 320.14 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.2014 mL | 16.0072 mL | 32.0143 mL |
| 5 mM | 0.6403 mL | 3.2014 mL | 6.4029 mL |
| 10 mM | 0.3201 mL | 1.6007 mL | 3.2014 mL |
-
1.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (320.14 mM); Clear solution; Need ultrasonic
References
- [1] Sun G, et al. Developmental toxicity and cardiac effects of butyl benzyl phthalate in zebrafish embryos. Aquat Toxicol. 2017;192:165-170.
- [2] Cui S, et al. Benzyl butyl phthalate (BBP) triggers the migration and invasion of hemangioma cells via upregulation of Zeb1. Toxicol In Vitro. 2019;60:323-329.
- [3] Wang YC, et al. Benzyl butyl phthalate promotes breast cancer stem cell expansion via SPHK1/S1P/S1PR3 signaling. Oncotarget. 2016;7(20):29563-29576.
Synonyms