[CAS NO. 87-17-2] Salicylanilide
PRODUCTS SPECIFICATIONS [87-17-2]
DESCRIPTION [87-17-2]
Overview
| MDL | MFCD00002212 |
|---|---|
| Molecular Weight | 213.23 |
| Molecular Formula | C13H11NO2 |
| SMILES | O=C(NC1=CC=CC=C1)C2=CC=CC=C2O |
1 Publications Citing Use of MCE
Summary
Salicylanilide demonstrates a wide range of biological activities including antiviral potency which can inhibit HIV virus by targeting HIV-1 integrase or reverse transcriptase .
IC50 & Target
|
HIV-1 |
In Vitro
Some Salicylanilides and salicylamides could inhibit HIV virus by targeting of HIV-1 integrase or reverse transcriptase. Hepatitis C virus is another virus, which can be potentially afflicted by Salicylanilides on the level of two enzymes-NS3 protease and NS5B RNA polymerase [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 170 mg/mL ( 797.26 mM ; Need ultrasonic and warming)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 4.6898 mL | 23.4489 mL | 46.8977 mL |
| 5 mM | 0.9380 mL | 4.6898 mL | 9.3795 mL |
| 10 mM | 0.4690 mL | 2.3449 mL | 4.6898 mL |
Synonyms