[CAS NO. 874485-32-2] 25(R,S)-Ruscogenin

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PRODUCTS SPECIFICATIONS [874485-32-2]

Catalog

HY-N5136

Brand

MCE

CAS

874485-32-2

DESCRIPTION [874485-32-2]

Overview

MDL	-
Molecular Weight	430.62
Molecular Formula	C27H42O4
SMILES	C[C@@]12[C@]3([H])[C@@](C[C@@]1([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H](C[C@H]5O)O)=CC4)C)([H])CC2)([H])O[C@]6(CCC(CO6)C)[C@H]3C

For research use only. We do not sell to patients.

Summary

Ruscogenin suppresses HCC metastasis by reducing the expression of MMP-2 , MMP-9 , uPA, VEGF and HIF-1α via regulating the PI3K/Akt/mTOR signaling pathway ^[1] . And Ruscogenin alleviates LPS-induced pulmonary endothelial cell apoptosis by su

Appearance

Solid

Source

Bacillus megaterium CGMCC 1.1741

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 232.22 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.3222 mL	11.6112 mL	23.2223 mL
5 mM	0.4644 mL	2.3222 mL	4.6445 mL
10 mM	0.2322 mL	1.1611 mL	2.3222 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (5.81 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (5.81 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (5.81 mM); Clear solution

* All of the co-solvents are available by MCE.