[CAS NO. 876707-99-2] Nucleoside-Analog-1
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PRODUCTS SPECIFICATIONS [876707-99-2]
Catalog
HY-77651
Brand
MCE
CAS
876707-99-2
DESCRIPTION [876707-99-2]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 267.20 |
| Molecular Formula | C9H9N5O5 |
| SMILES | O[C@@H]1[C@](CO)(N=[N+]=[N-])O[C@@H](N2C=C3)[C@H]1OC2=NC3=O |
For research use only. We do not sell to patients.
1 Publications Citing Use of MCE
Summary
Nucleoside-Analog-1 is a 4′-Azidocytidine analogue against Hepatitis C virus replication.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
In Vitro:
H 2 O : 1.89 mg/mL ( 7.07 mM ; Need ultrasonic)
Preparing
Stock Solutions
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.7425 mL | 18.7126 mL | 37.4251 mL |
| 5 mM | 0.7485 mL | 3.7425 mL | 7.4850 mL |
| 10 mM | --- | --- | --- |
*
Please refer to the solubility information to select the appropriate solvent.
In Vivo:
-
1.
Add each solvent one by one: PBS
Solubility: 8.33 mg/mL (31.18 mM); Clear solution; Need ultrasonic
*
All of the co-solvents are available by MCE.
References
- [1] Smith DB, et al. The design, synthesis, and antiviral activity of 4'-azidocytidine analogues against hepatitis C virus replication: the discovery of 4'-azidoarabinocytidine. J Med Chem. 2009 Jan 8;52(1):219-23.
- [2] Smith DB, et al. The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4'-azidocytidine against hepatitis C virus replication: the discovery of 4'-azido-2'-deoxy-2'-fluorocytidine and 4'-azido-2'-dideoxy-2',2'-difluorocytid
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