[CAS NO. 876708-01-9]  Nucleoside-Analog-2

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PRODUCTS SPECIFICATIONS [876708-01-9]

Catalog
HY-77652
Brand
MCE
CAS
876708-01-9

DESCRIPTION [876708-01-9]

Overview

MDL-
Molecular Weight285.21
Molecular FormulaC9H11N5O6
SMILESO[C@@H]1[C@](CO)(N=[N+]=[N-])O[C@@H](N2C(NC(C=C2)=O)=O)[C@H]1O

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE


Summary

Nucleoside-Analog-2 is a 4'-Azidocytidine analogue against Hepatitis C virus ( HCV ) replication.


In Vitro

Nucleoside-Analog-2 is a 4'-Azidocytidine analogue against Hepatitis C virus ( HCV ) replication. Reference to compound 12 [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 33.33 mg/mL ( 116.86 mM ; Need ultrasonic)

H 2 O : 20 mg/mL ( 70.12 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5062 mL 17.5309 mL 35.0619 mL
5 mM 0.7012 mL 3.5062 mL 7.0124 mL
10 mM 0.3506 mL 1.7531 mL 3.5062 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: PBS

    Solubility: 16.67 mg/mL (58.45 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

  • 2.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: 2.5 mg/mL (8.77 mM); Clear solution; Need ultrasonic

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (8.77 mM); Clear solution; Need ultrasonic

  • 4.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: 2.5 mg/mL (8.77 mM); Clear solution; Need ultrasonic

* All of the co-solvents are available by MCE.