[CAS NO. 886053-73-2]  NY2267

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PRODUCTS SPECIFICATIONS [886053-73-2]

Catalog
HY-134975
Brand
MCE
CAS
886053-73-2

DESCRIPTION [886053-73-2]

Overview

MDL-
Molecular Weight637.76
Molecular FormulaC38H43N3O6
SMILESO=C(OC(C)(C)C)COC1=CC=C2C=C(C(N(CC3=CC=C(OC)C=C3)C(C4=NC=CC=C4)=O)C(NC5CCCCC5)=O)C=CC2=C1

For research use only. We do not sell to patients.

Summary

NY2267 is a disruptor of Myc-Max interaction , with an IC 50 of 36.5 μM. NY2267 inhibits Myc- and Jun-induced transcriptional activation [1] .


In Vitro

NY2267 strongly inhibits oncogenic transformation induced by Myc [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Oil


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL ( 392.00 mM ; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5680 mL 7.8399 mL 15.6799 mL
5 mM 0.3136 mL 1.5680 mL 3.1360 mL
10 mM 0.1568 mL 0.7840 mL 1.5680 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.08 mg/mL (3.26 mM); Clear solution

* All of the co-solvents are available by MCE.