[CAS NO. 912288-64-3]  YHO-13351freebase

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PRODUCTS SPECIFICATIONS [912288-64-3]

Catalog
HY-12758A
Brand
MCE
CAS
912288-64-3

DESCRIPTION [912288-64-3]

Overview

MDL-
Molecular Weight483.62
Molecular FormulaC26H33N3O4S
SMILESN#C/C(C1=CC=C(OC)C(OC)=C1)=C\C2=CC=C(N3CCC(OC(CN(CC)CC)=O)CC3)S2

For research use only. We do not sell to patients.

Summary

YHO-13351 free base is the prodrug of YHO-13177, which is a potent and specific inhibitor of BCRP .


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 206.77 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0677 mL 10.3387 mL 20.6774 mL
5 mM 0.4135 mL 2.0677 mL 4.1355 mL
10 mM 0.2068 mL 1.0339 mL 2.0677 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (5.17 mM); Clear solution

* All of the co-solvents are available by MCE.