[CAS NO. 914638-30-5] IDO-IN-1

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PRODUCTS SPECIFICATIONS [914638-30-5]

Catalog

HY-79531

Brand

MCE

CAS

914638-30-5

For research use only. We do not sell to patients.

IDO-IN-1 is a potent indoleamine 2,3-dioxygenase ( IDO ) inhibitor with an IC ₅₀ of 59 nM.

IDO

59 nM (IC ₅₀ )

IDO

12 nM (IC ₅₀ , in HeLa cell)

IDO-IN-1 (Compound 5m) is a potent (HeLa IC ₅₀ =12 nM) inhibitor of IDO ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 120 mg/mL ( 379.64 mM ; Need ultrasonic)

Preparing
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Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 3 mg/mL (9.49 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 3 mg/mL (9.49 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 3 mg/mL (9.49 mM); Clear solution

* All of the co-solvents are available by MCE.