[CAS NO. 921-01-7] D-Cysteine
PRODUCTS SPECIFICATIONS [921-01-7]
DESCRIPTION [921-01-7]
Overview
| MDL | MFCD00066461 |
|---|---|
| Molecular Weight | 121.16 |
| Molecular Formula | C3H7NO2S |
| SMILES | N[C@H](CS)C(O)=O |
Summary
D-Cysteine is the D-isomer of cysteine and a powerful inhibitor of Escherichia coli growth. D-cysteine is mediated by D-amino acid oxidase to produce H 2 S and is a neuroprotectant against cerebellar ataxias. D-Cysteine could inhibit the growth and cariogenic virulence of dual-species biofilms formed by S. mutans and S. sanguinis [1] [2] [3] .
IC50 & Target
|
Human Endogenous Metabolite |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
H 2 O : 1 mg/mL ( 8.25 mM ; ultrasonic and warming and heat to 60°C)
DMSO : 1 mg/mL ( 8.25 mM ; ultrasonic and warming and heat to 60°C)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 8.2535 mL | 41.2677 mL | 82.5355 mL |
| 5 mM | 1.6507 mL | 8.2535 mL | 16.5071 mL |
| 10 mM | --- | --- | --- |
-
1.
Add each solvent one by one: PBS
Solubility: 7.69 mg/mL (63.47 mM); Clear solution; Need ultrasonic and warming and heat to 60°C
References
- [1] Seki T. Availability of D-cysteine as a protectant for cerebellar neurons. Nihon Yakurigaku Zasshi. 2019;154(3):133-137.
- [2] Soutourina J, et al. Role of D-cysteine desulfhydrase in the adaptation of Escherichia coli to D-cysteine. J Biol Chem. 2001 Nov 2;276(44):40864-72.
- [3] Guo X1, et al. Effect of D-cysteine on dual-species biofilms of Streptococcus mutans and Streptococcus sanguinis. Sci Rep. 2019 Apr 30;9(1):6689.
Synonyms