[CAS NO. 93-14-1] Guaifenesin

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PRODUCTS SPECIFICATIONS [93-14-1]

Catalog

HY-B0264

Brand

MCE

CAS

93-14-1

DESCRIPTION [93-14-1]

Overview

MDL	MFCD00016873
Molecular Weight	198.22
Molecular Formula	C10H14O4
SMILES	OCC(O)COC1=CC=CC=C1OC

For research use only. We do not sell to patients.

Summary

Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough ^[1] ^[2] .

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase
NCT01202279	Reckitt Benckiser Inc.\|Reckitt Benckiser LLC	Acute Upper Respiratory Track Infection	October 2009	Phase 4
NCT01364467	Virginia Commonwealth University\|Pfizer	Chronic Rhinitis	May 2011	Phase 2
NCT02879981	Hoffmann-La Roche	Bronchitis	November 10, 2016
NCT02902640	Hoffmann-La Roche	Bronchitis	November 15, 2016
NCT01576809	Novartis\|Novartis Consumer Health	Upper Respiratory Infections	March 2012	Phase 3
NCT00377403	Washington University School of Medicine\|National Institute of Allergy and Infectious Diseases (NIAID)	Acute Respiratory Infections\|Acute Rhinosinusitis	October 2006	Phase 4
NCT01562548	GlaxoSmithKline	Upper Back Pain	February 2012	Not Applicable
NCT01062256	Wyeth is now a wholly owned subsidiary of Pfizer	Infection	January 2010	Not Applicable
NCT03706300	Dr. Reddy´s Laboratories Limited	Healthy	December 2014	Phase 1
NCT01119534	Azidus Brasil	Cough	May 2011	Phase 3
NCT01257243	EMS	Cough	October 1, 2012	Phase 3
NCT00000752	National Institute of Allergy and Infectious Diseases (NIAID)\|Adams Laboratories\|Glaxo Wellcome	HIV Infections\|Sinusitis		Phase 2
NCT03213353	Johnson & Johnson Consumer and Personal Products Worldwide	Bioequivalence\|Healthy Volunteers	July 3, 2017	Phase 1
NCT01046136	Reckitt Benckiser Inc.\|Reckitt Benckiser LLC	Common Cold	December 2009	Phase 2
NCT02069665	Liaoning University of Traditional Chinese Medicine\|Beijing University of Chinese Medicine	Pneumonia	December 2011	Not Applicable
NCT01085721	Mantecorp Industria Quimica e Farmaceutica Ltd.	Viral Infections of the Upper Respiratory Tract		Phase 3
NCT01537081	Reckitt Benckiser LLC	Acute Upper Respiratory Tract Infection	September 2011	Phase 2\|Phase 3

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 504.49 mM ; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.0449 mL	25.2245 mL	50.4490 mL
5 mM	1.0090 mL	5.0449 mL	10.0898 mL
10 mM	0.5045 mL	2.5224 mL	5.0449 mL

* Please refer to the solubility information to select the appropriate solvent.

References

Synonyms

1,2-Propanediol, 3-(2-methoxyphenoxy)-

1,2-Propanediol, 3-(o-methoxyphenoxy)-

3-(2-Methoxyphenoxy)-1,2-propanediol

SL 90

Aeronesin

Aresol

Creson

1,2-Dihydroxy-3-(2-methoxyphenoxy)propane

Dilyn

Glycerin guaiacolate

Glycerol guaiacolate

Glycerol α-(o-methoxyphenyl)ether

Glyceryl guaiacolate

α-Glyceryl guaiacolate ether

Glyceryl guaiacyl ether

Glycotuss

α-Glyceryl guaiacol ether

Guaiacuran

Guaiacurane

Guaiacyl glyceryl ether

Guaiamar

Guaianesin

Guaiphenesin

Guaiphenesine

Guajacuran

Guayanesin

3-(o-Methoxyphenoxy)-1,2-propanediol

o-Methoxyphenyl glyceryl ether

Methphenoxydiol

Myocaine

Neuroton

Neurotone

Oresol

Oreson

Reorganin

Respenyl

Resyl

Ritussin

Guaiacol glyceryl ether

Glycerylguaiacol

Guaiacol glycerol ether

Glyceryl guaiacolate ether

Glycerol α-guaiacyl ether

Glycerol α-(2-methoxyphenyl) ether

XL 90

Myoscain

Relaxil G

Calmipan

Tenntuss

Tulyn

Sirotol

Guaiacol glycerin ether

Guaifenesin

Muskurelax

Myocain

Hytuss

Miocurin

Guanar

My 301

Robitussin

Glyceryl guaiacol ether

Trecid

Hustosil

racemic-Guaifenesin

Guaifenesine

Tenntus

Actifed C

Equicol

Colrex Expectorant

Amonidren

2-G

Glycodex

NSC 62112

Organidin NR

Mucinex

Giafen