[CAS NO. 939981-37-0]  p53andMDM2proteins-interaction-inhibitor(chiral)

Ships within Stock Price Qty Total
$0.00
$0.00
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [939981-37-0]

Catalog
HY-70027
Brand
MCE
CAS
939981-37-0

DESCRIPTION [939981-37-0]

Overview

MDLMFCD14584417
Molecular Weight734.75
Molecular FormulaC40H49Cl2N5O4
SMILESO=C(N1CCN(CC(N2CCOCC2)=O)CC1)N3[C@](C)(C4=CC=C(Cl)C=C4)[C@](C)(C5=CC=C(Cl)C=C5)N=C3C6=CC=C(C(C)(C)C)C=C6OCC

For research use only. We do not sell to patients.

Summary

p53 and MDM2 proteins-interaction-inhibitor (chiral) (Compound 32) is an inhibitor of the interaction between p53 and MDM2 proteins.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL ( 68.05 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3610 mL 6.8050 mL 13.6101 mL
5 mM 0.2722 mL 1.3610 mL 2.7220 mL
10 mM 0.1361 mL 0.6805 mL 1.3610 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 3.25 mg/mL (4.42 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 3.25 mg/mL (4.42 mM); Clear solution

* All of the co-solvents are available by MCE.