[CAS NO. 959151-50-9] PF750
PRODUCTS SPECIFICATIONS [959151-50-9]
DESCRIPTION [959151-50-9]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 345.44 |
| Molecular Formula | C22H23N3O |
| SMILES | O=C(NC1=CC=CC=C1)N(CC2)CCC2CC3=CN=C4C(C=CC=C4)=C3 |
Summary
PF 750 is a selective and covalent fatty acid amide hydrolase (FAAH) inhibitor, with IC 50 s varied from 16.2-595 nM in different pre-incubation times. Covalently modifies the enzyme’s active site serine nucleophile [1] .
IC50 & Target
IC50: 16.2-595 nM (FAAH) [1] .
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 289.49 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.8949 mL | 14.4743 mL | 28.9486 mL |
| 5 mM | 0.5790 mL | 2.8949 mL | 5.7897 mL |
| 10 mM | 0.2895 mL | 1.4474 mL | 2.8949 mL |