[CAS NO. 960404-86-8]  Dapagliflozinimpurity

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PRODUCTS SPECIFICATIONS [960404-86-8]

Catalog
HY-128723
Brand
MCE
CAS
960404-86-8

DESCRIPTION [960404-86-8]

Overview

MDLMFCD32215328
Molecular Weight424.87
Molecular FormulaC21H25ClO7
SMILESO[C@]1(C2=CC=C(Cl)C(CC3=CC=C(OCC)C=C3)=C2)[C@@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)O

For research use only. We do not sell to patients.

Summary

Dapagliflozin impurity is an enantiomer of Dapagliflozin which is a sodium-glucose transporter 2 inhibitor [1] .


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL ( 58.84 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3537 mL 11.7683 mL 23.5366 mL
5 mM 0.4707 mL 2.3537 mL 4.7073 mL
10 mM 0.2354 mL 1.1768 mL 2.3537 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 1.43 mg/mL (3.37 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 1.43 mg/mL (3.37 mM); Clear solution

* All of the co-solvents are available by MCE.