[CAS NO. 9004-66-4]  Iron dextran

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PRODUCTS SPECIFICATIONS [9004-66-4]

Catalog
HY-107928
Brand
MCE
CAS
9004-66-4

DESCRIPTION [9004-66-4]

Overview

MDL-
Molecular Weight-
Molecular Formula-
SMILES[Iron dextran]

For research use only. We do not sell to patients.

Summary

Iron dextran (Fe dextran) can be used in the study of iron-deficiency anemia in animals [1] [2] .


In Vivo

Iron dextran (FeDex, IP, 4 weeks, 300 μL of 10 mg) treatment does not increase NSR iron but causes iron-trapping in the tetinal vasculature [1] .
Four weeks of IP FeDex injection in 2-month-old WT mice leads to iron accumulation in the RPE and rVECs, but did not increase NSR iron or induce photoreceptor degeneration [1] .

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wild-type (WT) and RS- Hepc KO mice [1] .
Dosage: IP.
Administration: 300 μL of 10 mg daily for 5 days each week for 2 or 4 weeks.
Result: Markedly elevated iron levels in 2 and 4 weeks of FeDex-injection groups, by 365.4-fold and 405.4-fold, respectively, compared with PBS controls.

Clinical Trial

NCT Number Sponsor Condition Start Date Phase
NCT03279536 Woman´s Health University Hospital, Egypt
Iron Deficiency Anemia
November 1, 2017 Phase 1|Phase 2
NCT00704028 American Regent, Inc.
Anemia
June 2008 Phase 3
NCT01307007 American Regent, Inc.
Iron Deficiency Anemia
September 2010 Phase 2

Appearance

Liquid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

H 2 O : ≥ 50 mg/mL

* "≥" means soluble, but saturation unknown.