[CAS NO. 134523-00-5] Atorvastatin

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PRODUCTS SPECIFICATIONS [134523-00-5]

Catalog

HY-B0589

Brand

MCE

CAS

134523-00-5

DESCRIPTION [134523-00-5]

Overview

MDL	-
Molecular Weight	558.64
Molecular Formula	C33H35FN2O5
SMILES	O=C(C(C(C1=CC=CC=C1)=C(C2=CC=C(F)C=C2)N3CC[C@@H](O)C[C@@H](O)CC(O)=O)=C3C(C)C)NC4=CC=CC=C4

For research use only. We do not sell to patients.

27 Publications Citing Use of MCE

Summary

Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin inhibits human SV-SMC proliferation and invasion with IC ₅₀ s of 0.39 μM and 2.39 μM, respectively ^[1] ^[2] ^[3] .

In Vitro

Atorvastatin treatment decreases apoptosis of myocardial cells by down-regulating GRP78, caspase-12 and CHOP expression in myocardial cells after myocardial infarction, and the endoplasmic reticulum (ER) stress is activated in response to heart failure and angiotensin II (Ang II) stimulation ^[4] .

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Atorvastatin (20-30 mg/kg; oral gavage; once a day; for 28 days; ApoE ^−/− mice) treatment significantly reduces endoplasmic reticulum (ER) stress signaling proteins, the number of apoptotic cells, and the activation of Caspase12 and Bax in the Ang II-induced ApoE-/- mice. Proinflammatory cytokines such as IL-6 , IL-8, IL-1β are all remarkably inhibited after Atorvastatin treatment ^[5] .

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Forty 8-week-old ApoE ^−/− mice induced with angiotensin II (Ang II) ^[5]
Dosage:	20 mg/kg, 30 mg/kg
Administration:	Oral gavage; once a day; for 28 days
Result:	Significantly reduced ER stress signaling proteins, the number of apoptotic cells, and the activation of Caspase12 and Bax in the Ang II-induced ApoE ^−/− mice. Proinflammatory cytokines such as IL-6, IL-8, IL-1β were all remarkably inhibited.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase
NCT00124397	University of Southern Denmark\|Pfizer	Type 2 Diabetes Mellitus	July 2001	Phase 4
NCT00329173	AstraZeneca	Hypercholesterolaemia	November 2003	Phase 3
NCT03692754	Shandong University	Immune Thrombocytopenia\|Purpura, Thrombocytopenic	November 1, 2021	Phase 2\|Phase 3
NCT00432354	Buddhist Tzu Chi General Hospital\|Pfizer	Systemic Lupus Erythematosus	March 2007	Phase 2\|Phase 3
NCT03186404	University Health Network, Toronto\|Mount Sinai Hospital, Canada\|Unity Health Toronto\|Sunnybrook Health Sciences Centre\|Scarborough General Hospital	Cancer\|Heart Failure\|Cardiotoxicity	May 10, 2018	Phase 2
NCT03760848	Galmed Pharmaceuticals Ltd\|Hammersmith Medicines Research\|Analyst Research Laboratories\|Alderley Analytical\|Diamond Pharma Services Regulatory Affairs Consultancy	Healthy	November 12, 2018	Phase 1
NCT05705804	Yonsei University	Dyslipidemias\|Atherosclerotic Cardiovascular Disease	June 13, 2023	Not Applicable
NCT00194402	University of Washington\|Upsher-Smith Laboratories	Dyslipidemia	August 2003	Phase 4
NCT03820466	Dr. med. Mahir Karakas\|Universitätsklinikum Hamburg-Eppendorf	Acute Chest Syndrome	February 21, 2020	Phase 3
NCT03745300	Government Dental College and Research Institute, Bangalore	Chronic Periodontitis Wth Diabetes Mellitus	March 3, 2017	Phase 2\|Phase 3
NCT01964326	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Hypercholesterolemia	October 2013	Phase 3
NCT02286544	Karolinska Institutet\|University Hospital, Linkoeping	Myocardial Infarction\|Inflammation\|Acute Coronary Syndrome (ACS)\|Reperfusion Injury	October 2014	Phase 1
NCT00782184	Organon and Co	Hypercholesterolemia	November 2008	Phase 3
NCT00559962	Aegerion Pharmaceuticals, Inc.	Hyperlipidemia	October 2007	Phase 2
NCT00701220	Philip Binkley\|Pfizer\|Ohio State University	Cardiovascular Disease\|Cardiomyopathy\|Heart Disease\|Myocardial Disease\|Myocardial Ischemia	April 2007	Phase 4
NCT03433196	Zhejiang Hisun Pharmaceutical Co. Ltd.	Hypercholesterolemia in Coronaory Heart Disease	June 7, 2016	Phase 3
NCT02967653	Lady Davis Institute	Lithium Use, Nephrogenic Diabetes Insipidus	July 13, 2017	Phase 2
NCT01138072	GlaxoSmithKline	Infection, Human Immunodeficiency Virus	June 2010	Phase 1
NCT01765023	HK inno.N Corporation	Healthy	October 2012	Phase 1
NCT00647543	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Dyslipidemias	August 2003	Phase 4
NCT01299597	GlaxoSmithKline	Sleep Disorders	January 18, 2010	Phase 1
NCT05251129	Montefiore Medical Center	Vasculopathy	January 2024	Not Applicable
NCT00343655	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Cardiovascular Diseases	January 2007	Phase 3
NCT02740699	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Cardiovascular Disease	April 11, 2016	Phase 4
NCT00004564	National Center for Research Resources (NCRR)	Hypercholesterolemia\|Thrombosis		Not Applicable
NCT00239330	AstraZeneca	Hypercholesteremia	June 2003	Phase 3
NCT05895123	Damanhour University\|Alexandria University	ST-segment Elevation Myocardial Infarction	October 1, 2022	Phase 2
NCT01518231	Zhejiang Hospital\|Zhejiang University	Stroke	January 2012	Phase 1
NCT00344019	Beth Israel Deaconess Medical Center\|Pfizer	Coronary Disease	May 2006	Phase 4
NCT00368589	GlaxoSmithKline	Atherosclerotic Carotid Disease\|Atheroma\|Atherosclerosis	July 2006
NCT05342974	University of Utah\|Grand Challenges Canada	Abortion Early	April 19, 2022	Early Phase 1
NCT05870007	Taipei Medical University Shuang Ho Hospital\|University of Southern California	Autosomal Dominant Polycystic Kidney Disease\|Chronic Kidney Diseases	May 2023	Phase 2
NCT01126684	Aristotle University Of Thessaloniki	Hypertension\|Hypercholesterolemia	June 2008	Not Applicable
NCT00094172	National Institute of Allergy and Infectious Diseases (NIAID)\|Immune Tolerance Network (ITN)	Multiple Sclerosis	May 2005	Phase 2
NCT00115817	Brigham and Women´s Hospital	Atherosclerosis	June 2005	Phase 3
NCT04945122	Chinese Academy of Medical Sciences, Fuwai Hospital	Acute Myocardial Infarction\|Glucose Metabolism Disorders	October 1, 2015	Phase 4
NCT01185236	Seoul National University Hospital\|Merck Sharp & Dohme LLC	Type 2 Diabetes Mellitus Without Insulin Treatment	September 2010	Phase 4
NCT00150722	University of Calgary\|Heart and Stroke Foundation of Ontario	Atherosclerosis	September 2005	Phase 3
NCT00017758	National Institute of Allergy and Infectious Diseases (NIAID)	HIV Infections\|HIV Seronegativity\|Lipodystrophy		Phase 1
NCT00701883	CymaBay Therapeutics, Inc.	Hyperlipidemia	August 2007	Phase 2
NCT02943590	Massachusetts General Hospital\|Dana-Farber Cancer Institute\|Brigham and Women´s Hospital	Heart Failure	January 13, 2017	Phase 2
NCT04380402	Mount Auburn Hospital	COVID-19	June 25, 2020	Phase 2
NCT00065806	Laura Schanberg\|Duke University	Lupus Erythematosus, Systemic	September 2003	Phase 3
NCT02156492	Eli Lilly and Company	Healthy Volunteers	June 2014	Phase 1
NCT02260648	Eli Lilly and Company	Hypercholesterolemia	January 2015	Phase 3
NCT02114346	Isfahan University of Medical Sciences	Contrast-Induced Nephropathy	July 2013	Phase 2\|Phase 3
NCT03882996	Organon and Co	Hypercholesterolemia	October 6, 2000	Phase 3
NCT05483010	Washington University School of Medicine	Clonal Cytopenia of Undetermined Significance\|Myelodysplastic Syndromes	June 30, 2023	Phase 2
NCT02522117	Instituto Mexicano del Seguro Social	Renal Insufficiency	August 2015	Phase 3
NCT00993915	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Cardiovascular Diseases\|Coronary Artery Disease	April 2010
NCT04747847	University of California, San Diego\|National Heart, Lung, and Blood Institute (NHLBI)	Kawasaki Disease	October 9, 2017	Early Phase 1
NCT01768481	Université de Montréal\|Pfizer	Obesity\|Dyslipidemia	January 2004	Phase 3
NCT02679261	Hospital Universitari Vall d´Hebron Research Institute	Bicuspid Aortic Valve	June 2016	Phase 3
NCT00767572	University of California, San Francisco\|American Heart Association	Coarctation of the Aorta	August 2008	Phase 4
NCT01617772	Tehran University of Medical Sciences	Non-alcoholic Steatohepatitis	January 1, 2016	Phase 2
NCT02984982	Sanofi\|Regeneron Pharmaceuticals	Hypercholesterolemia\|Acute Coronary Syndrome	November 15, 2016	Phase 4
NCT03355027	Cambridge University Hospitals NHS Foundation Trust\|University of Cambridge	Atherosclerosis\|Cardiovascular Diseases	November 30, 2017	Not Applicable
NCT00181181	Johns Hopkins University\|American Heart Association\|Procris Pharmaceuticals	Hypertension	May 2003	Phase 4
NCT05583643	Misr University for Science and Technology	Periodontitis	December 7, 2021	Phase 1
NCT01072097	University of Oulu\|Pfizer	Polycystic Ovary Syndrome	September 2006	Not Applicable
NCT00185731	Dean Felsher\|The Leukemia and Lymphoma Society\|Damon Runyon Cancer Research Foundation\|Burroughs Wellcome\|Stanford University	Leukemia\|Lymphoma, Non-Hodgkin	April 2005	Phase 2
NCT00519363	The Center for Rheumatic Disease, Allergy, & Immunology\|Saint Luke´s Health System	Systemic Lupus Erythematosus	September 2007	Phase 1\|Phase 2
NCT04333407	Imperial College London	COVID-19	April 3, 2020	Not Applicable
NCT01071993	University of Oklahoma	Nephropathy	March 2010	Not Applicable
NCT00663234	International Maternal Pediatric Adolescent AIDS Clinical Trials Group\|National Institute of Allergy and Infectious Diseases (NIAID)\|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	HIV Infections\|Hyperlipidemia	August 2009	Phase 1\|Phase 2
NCT05563389	Tanta University	Quality of Life	June 15, 2022	Phase 2\|Phase 3
NCT01795937	Boehringer Ingelheim	Healthy	February 2013	Phase 1
NCT01635946	Astellas Pharma Global Development, Inc.\|Basilea Pharmaceutica International Ltd\|Astellas Pharma Inc	Pharmacokinetics of Isavuconazole\|Pharmacokinetics of Atorvastatin\|Healthy Volunteers	August 2012	Phase 1
NCT01447797	Hanmi Pharmaceutical Company Limited	Healthy	September 2011	Phase 1
NCT01600170	University of Pennsylvania	HIV Dementia	January 2013	Phase 4
NCT01748279	Medical University of Bialystok	COPD	December 2012	Phase 4
NCT02029118	Chengdu University of Traditional Chinese Medicine	Stable Angina Pectoris	October 2012	Early Phase 1
NCT03460808	Peking University People´s Hospital	Immune Thrombocytopenia	March 10, 2018	Phase 1\|Phase 2
NCT02518503	Canadian Network for Observational Drug Effect Studies, CNODES\|Drug Safety and Effectiveness Network, Canada\|Canadian Institutes of Health Research (CIHR)	Diabetes Mellitus, Type 2\|Cardiovascular Disease	July 2012
NCT00716846	Hamamatsu University	Healthy Volunteers	June 2006	Not Applicable
NCT00276484	Organon and Co	Hypercholesterolemia	February 2006	Phase 3
NCT01220973	Rutgers, The State University of New Jersey\|Rutgers Cancer Institute of New Jersey\|National Cancer Institute (NCI)	Prostate Cancer	February 2009	Phase 2
NCT02566187	Boryung Pharmaceutical Co., Ltd	Hypertension\|Hyperlipidemia	August 2015	Phase 1
NCT00487994	Takeda	Dyslipidemia	November 2004	Phase 3
NCT00259662	Yale University\|Washington Mutual Foundation	Gynecologic Oncological Pelvic+Abdominal Surgery	November 2005	Not Applicable
NCT02157337	Yonsei University	Aortic Surgery\|Acute Kidney Injury	March 12, 2014	Phase 4
NCT01154036	Organon and Co	Hypercholesterolemia	July 2010	Phase 3
NCT00276458	Organon and Co	Hypercholesterolemia	February 2006	Phase 3
NCT01442987	Hanmi Pharmaceutical Company Limited	Hypertension\|Hyperlipidemia	May 2011	Phase 3
NCT02659397	Esperion Therapeutics, Inc.	Hyperlipidemia	December 2015	Phase 2
NCT01236365	Nemours Children´s Clinic\|Pfizer\|Medtronic\|Quest Diagnostics-Nichols Insitute	Diabetes Mellitus, Insulin-Dependent\|Hypercholesterolemia	October 2010	Phase 3
NCT01720719	Xin Gao\|Pfizer\|Fudan University	Fatty Liver\|Dyslipidemias\|Diabetes Mellitus	May 2013	Phase 4
NCT05551624	Hospital Civil de Guadalajara	Primary Immune Thrombocytopenia	July 4, 2018	Early Phase 1
NCT01665235	RenJi Hospital	Blood Pressure Variability\|Intracranial Artery Stenosis	August 2012	Not Applicable
NCT02084069	Urmia University of Medical Sciences	Heart Valve Diseases	January 2013	Phase 3
NCT02125682	Hotel Dieu de France Hospital\|Nouvelle Société Française d´Athérosclérose\|Pfizer	Dyslipidemia in Patients With Diabetes Mellitus	January 2012	Phase 4
NCT04631536	Lebanese American University Medical Center	Covid19	January 10, 2021	Phase 3
NCT00653588	AstraZeneca	Hypercholesterolemia\|Coronary Heart Disease	April 2003	Phase 3
NCT00292201	Queen´s University\|The Physicians´ Services Incorporated Foundation\|Ontario Lung Association	Asthma	February 2006	Phase 2
NCT01236430	Organon and Co	Hyperlipidemia	February 2011	Phase 1
NCT01980823	Columbia University	Breast Cancer\|Breast Tumors\|Cancer of Breast	October 2013	Early Phase 1
NCT01062802	University of Hull	Abdominal Aortic Aneurysm	January 2005	Phase 4
NCT01541943	HanAll BioPharma Co., Ltd.	Essential Hypertension\|Hyperlipidemia	March 2012	Phase 3
NCT00344955	Regional Hospital Holstebro	Healthy	January 2003	Phase 4
NCT03830164	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Male Erectile Disorder\|Prostate Adenocarcinoma\|Erectile Dysfunction, CTCAE\|Impotence	November 20, 2019	Phase 2
NCT02023892	Sun Yat-sen University	Endothelium\|Hydroxymethylglutaryl-CoA Reductase Inhibitors	June 2014	Phase 4
NCT00932048	Korea University	Type 2 Diabetes\|Atherosclerosis	August 2011	Not Applicable
NCT00136981	Pfizer	Hypercholesterolemia, Familial\|Hyperlipidemia	December 2003	Phase 3
NCT04679376	Mayo Clinic	NASH - Nonalcoholic Steatohepatitis	January 25, 2023	Phase 2
NCT00611143	Samsung Medical Center	Coronary Artery Bypass	May 2006	Not Applicable
NCT01543555	Hospital do Coracao	Myocardial Infarction\|Peripheral Vascular Disease\|Aortic Aneurism	November 2012	Phase 3
NCT02380625	Clinical Research Management, Inc.\|Bill and Melinda Gates Foundation\|Duke University\|University of Sierra Leone\|Syneos Health\|University of North Carolina	Ebola Virus Disease	April 2015	Phase 1\|Phase 2
NCT00490698	M.D. Anderson Cancer Center\|Novartis Pharmaceuticals	Kidney Cancer\|Renal Cell Carcinoma	October 2006	Phase 2
NCT02114099	National Taiwan University Hospital\|National Science Council, Taiwan	Kawasaki Disease\|Aneurysm, Coronary	June 2007	Phase 2
NCT01780740	University of Oxford	Disorder; Heart, Functional, Postoperative, Cardiac Surgery\|Cardiac Insufficiency Following Cardiac Surgery\|Atrial Fibrillation\|Ischaemia-reperfusion Injury	January 2012	Phase 4
NCT00141232	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Churchill Hospital\|Pfizer	Diabetes, Type 2	November 2004	Phase 4
NCT00327418	Pfizer\|Diabetes UK\|Department of Health, United Kingdom	Major Coronary Event\|Cerebrovascular Accident\|Coronary Artery Bypass Graft\|Angina, Unstable\|Revascularization	January 1997	Phase 4
NCT00715273	University of Washington\|National Heart, Lung, and Blood Institute (NHLBI)\|Pfizer\|Abbott\|Daiichi Sankyo, Inc.\|Upsher-Smith Laboratories	Coronary Artery Disease\|Carotid Artery Diseases\|Atherosclerosis	May 1, 2001	Phase 4
NCT04245046	Midas Pharma GmbH	Healthy Volunteers	January 18, 2019	Phase 1
NCT00214630	AstraZeneca	Acute Coronary Syndromes	December 2003	Phase 3
NCT00811330	University Hospital, Strasbourg, France	Aortic Valve Stenosis\|Ventricular Hypertrophy	December 2008	Phase 3
NCT00570752	Bristol-Myers Squibb	Vascular Diseases	December 2008	Phase 2
NCT02776956	xieruiqin\|The Second Hospital of Hebei Medical University	Atrial Fibrillation	April 2016	Not Applicable
NCT01988571	Wake Forest University Health Sciences\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Breast Cancer\|Lymphoma	February 1, 2014	Phase 2
NCT00736463	Oregon Health and Science University\|Merck Sharp & Dohme LLC\|Oregon State University\|Indiana University	HDL Cholesterol	January 2005	Phase 4
NCT00079638	Kos Pharmaceuticals	Dyslipidemia\|Coronary Heart Disease\|Atherosclerosis\|Stroke\|Diabetes	April 2004	Phase 4
NCT00967252	Ottawa Hospital Research Institute	Inflammation\|Infection\|Endothelial Function	November 2008
NCT03660293	Tanta University	Diabetes Mellitus, Type 1	April 1, 2017	Not Applicable
NCT01187992	San Filippo Neri General Hospital\|Associazione Nazionale Medici Cardiologi Ospedalieri	Acute Coronary Syndrome\|Coronary Artery Disease	September 2003	Phase 3
NCT00465088	Abbott	Hyperlipidemia\|Mixed Dyslipidemia	April 2007	Phase 3
NCT02080455	Aegerion Pharmaceuticals, Inc.	Effect of Atorvastatin on the Pharmacokinetics of Lomitapide	January 27, 2014	Phase 1
NCT01043380	Kumamoto University	Hypercholesterolemia\|Coronary Artery Disease	January 2010	Phase 4
NCT00143676	Takeda	Hypercholesterolemia	August 2005	Phase 3
NCT02681653	Sanjay Gandhi Postgraduate Institute of Medical Sciences	Septic Shock	January 2012	Not Applicable
NCT02901379	National Cardiovascular Center Harapan Kita Hospital Indonesia	Myocardial Edema	October 2016	Phase 3
NCT00640744	Baylor College of Medicine\|Pfizer	Atherosclerosis	February 2006	Phase 4
NCT04453735	Vestre Viken Hospital Trust\|The Hospital of Vestfold\|Oslo University Hospital	Statin Adverse Reaction	August 19, 2020	Phase 4
NCT00535405	Organon and Co\|Merck Shering-Plough JV Study	Hypercholesterolemia	November 2007	Phase 3
NCT00137462	Pfizer	Hyperlipidemia	November 2004	Phase 3
NCT01040936	Shanghai Jiao Tong University School of Medicine	Acute Coronary Syndrome	May 2010	Phase 4
NCT01922687	Shanghai Institute of Hypertension	Arterial and Arteriolar Disorders	April 2011	Phase 4
NCT00645424	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Hyperlipidemias	December 2003	Phase 4
NCT05076019	Odense University Hospital\|Odense Patient Data Explorative Network\|GCP-unit at Odense University Hospital	Postoperative Atrial Fibrillation	February 1, 2022	Not Applicable
NCT01115985	Astellas Pharma Inc	Healthy\|Pharmacokinetics of Atorvastatin	March 2010	Phase 1
NCT00462748	Organon and Co	Hypercholesterolemia	March 2007	Phase 3
NCT02113540	Isfahan University of Medical Sciences	Contrast Induced Nephropathy	January 2012	Phase 3
NCT02749578	Madrigal Pharmaceuticals, Inc.\|Celerion	Healthy	April 2016	Phase 1
NCT00620542	AstraZeneca\|The Cleveland Clinic	Coronary Atherosclerosis	January 2008	Phase 3
NCT00722956	AstraZeneca	Healthy Volunteers\|Pharmacokinetics	July 2008	Phase 1
NCT02245269	Boehringer Ingelheim	Healthy	July 2003	Phase 1
NCT00795912	St Vincent´s University Hospital, Ireland\|University of Dublin, Trinity College\|University College Dublin\|University College Cork	Heart Failure	May 2003	Phase 4
NCT03228017	NYU Langone Health	Cardiovascular Diseases\|Myocardial Infarction\|Atherosclerotic Cardiovascular Disease\|Thrombotic Vascular Disease	August 1, 2017	Phase 4
NCT00791648	Vanderbilt University Medical Center	Acute Kidney Injury\|Post-Operative Delirium\|Icu Delirium\|Acute Renal Failure\|Delirium	July 2009	Not Applicable
NCT01293097	Peking University First Hospital	Non-ST Segment Elevation Myocardial Infarction\|Unstable Angina Pectoris\|Stable Angina Pectoris	June 2010	Phase 4
NCT00446940	Bader, Ted, M.D.	Hepatitis C	December 2006	Phase 2
NCT00861861	Kumamoto University	Hypercholesterolemia\|Coronary Artery Disease	September 2008	Phase 4
NCT04685642	Taipei Veterans General Hospital, Taiwan	Mood Disorder	August 24, 2020	Phase 4
NCT03037372	Makerere University\|University of Oxford\|Case Western Reserve University	HIV Infection	June 1, 2017	Phase 3
NCT02135029	Pfizer	Hyperlipidemia	June 2014	Phase 3
NCT00457340	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Arrhythmia	February 2000	Phase 4
NCT02984293	University of Dundee\|NHS Tayside	Drug Intolerance	April 17, 2017	Phase 4
NCT00678522	Regional Hospital Holstebro\|Medical Research	Healthy Subjects	September 2007	Phase 4
NCT05028829	Raymond Chung\|University of Texas Southwestern Medical Center\|Massachusetts General Hospital	Liver Fibroses\|Cirrhosis	May 10, 2023	Phase 2
NCT01730040	Regeneron Pharmaceuticals\|Sanofi	Hypercholesterolemia	October 2012	Phase 3
NCT05049603	University of Pisa\|Università degli Studi dell´Insubria\|University of Catania\|University of Messina	Graves´ Orbitopathy	January 1, 2024	Phase 3
NCT00133380	Eli Lilly and Company	Hypercholesterolemia	July 2005	Phase 2
NCT00134264	Pfizer	Coronary Disease\|Diabetes Mellitus	July 2004	Phase 3
NCT01086020	Shanghai Jiao Tong University School of Medicine	Coronary Artery Disease	January 2010	Phase 4
NCT03769870	Handok Inc.	Diabete Mellitus	January 11, 2019	Phase 1
NCT00345202	Regional Hospital Holstebro	Healthy	September 2004	Phase 4
NCT00491530	Abbott	Mixed Dyslipidemia	June 2007	Phase 3
NCT02060032	Government Dental College and Research Institute, Bangalore	Chronic Periodontitis	February 2013	Phase 2\|Phase 3
NCT00741715	Sanofi	Hypercholesterolemia	August 2008	Phase 3
NCT04721795	Obafemi Awolowo University Teaching Hospital\|University Hospital Birmingham NHS Foundation Trust\|Cures Within Reach	Tuberculosis, Pulmonary\|Tuberculosis	January 19, 2021	Phase 2\|Phase 3
NCT03289429	Assiut University	Arrhythmias	September 24, 2017	Phase 4
NCT02030054	University of Roma La Sapienza	Coronary Artery Disease	January 2015	Phase 4
NCT00362934	Solvay Pharmaceuticals	Hyperlipidemia	October 2006	Phase 3
NCT04718155	Assiut University	Traumatic Brain Injury	March 1, 2021	Not Applicable
NCT01837069	NYU Langone Health	Osteoarthritis\|Cardiovascular Disease	February 2014	Phase 4
NCT04900155	Penza State University	STEMI\|Covid19\|NSTEMI	November 20, 2020	Not Applicable
NCT00914017	University of Vermont\|Breast Cancer Research Foundation\|Cancer and Leukemia Group B	Breast Cancer	January 2005	Phase 2
NCT01351025	AIDS Clinical Trials Group\|National Institute of Allergy and Infectious Diseases (NIAID)\|Pfizer	HIV-1 Infection	April 14, 2011	Phase 2
NCT01779687	Radboud University Medical Center\|Merck Sharp & Dohme LLC	HIV\|Hypercholesterolaemia	March 2013	Phase 1
NCT03768427	Organon and Co	Hypercholesterolemia	May 27, 2019	Phase 3
NCT00540293	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Dyslipidemias	October 2007	Phase 4
NCT05912686	Zhongda Hospital	Mechanical Thrombectomy\|Acute Ischemic Stroke	July 1, 2023	Phase 4
NCT01341730	The Catholic University of Korea\|Jeil Pharmaceutical Co., Ltd.	Atherosclerosis\|Coronary Artery Disease	June 2011	Phase 4
NCT01375075	Eli Lilly and Company	Dyslipidemias	June 2011	Phase 2
NCT01821404	Tampere University Hospital\|Tampere University\|Fimlab laboratories\|University of Eastern Finland\|Finnish Cultural Foundation	Prostatic Neoplasms	August 2012	Phase 2
NCT02432534	Centre Hospitalier Universitaire de Nice	Vitiligo	May 2015	Phase 2
NCT00442845	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Coronary Arteriosclerosis\|Diabetes Mellitus, Type 2\|Cerebrovascular Accident\|Dyslipidemia\|Peripheral Vascular Disease	January 2003	Phase 4
NCT04789057	Medical University of Bialystok\|Medical Research Agency, Poland	Copd\|COPD Exacerbation\|Smoking\|Gene Expression\|Atorvastatin	February 11, 2022	Phase 4
NCT03510715	Sanofi\|Regeneron Pharmaceuticals	Hypercholesterolemia	August 31, 2018	Phase 3
NCT00609063	Hartford Hospital\|National Heart, Lung, and Blood Institute (NHLBI)	Hydroxymethylglutaryl-CoA Reductase Inhibitors\|Muscular Diseases	January 2008	Not Applicable
NCT00199745	Oslo University Hospital\|University of Oslo School of Pharmacy	Muscular Diseases	October 2005	Phase 4
NCT00505336	St Vincent´s University Hospital, Ireland	Diastolic Heart Failure	April 2006	Not Applicable
NCT01175148	West Virginia University	Graft vs Host Disease	July 2010	Phase 2
NCT00004466	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)\|Southwest Pediatric Nephrology Study Group	Nephrotic Syndrome\|Hyperlipidemia	October 1998	Phase 2
NCT04347434	Penza State University	Myocardial Infarction, Acute\|Myocardial Strain\|Arterial Stiffness\|Quality of Life	February 12, 2020	Phase 4
NCT05681273	Chipscreen Biosciences, Ltd.	T2DM	February 17, 2023	Phase 1
NCT00463827	NHS Greater Clyde and Glasgow\|University of Glasgow\|Medical Research Council	Asthma\|COPD\|Smoking	August 2007	Phase 2
NCT01208701	Erling Bjerregaard Pedersen\|Regional Hospital Holstebro	Nephropathy\|Cardiovascular Diseases\|Diabetes Mellitus	May 2010	Phase 2
NCT03929744	Eli Lilly and Company	Healthy	June 12, 2019	Phase 1
NCT01013103	Hippocration General Hospital	Coronary Artery Disease\|HMG-CoA Reductase Inhibitor Toxicity\|Atherosclerosis\|Oxidative Stress\|Endothelial Dysfunction	October 2007	Phase 4
NCT05806723	Hopital La Rabta	Diabetes Mellitus, Type 2\|Dyslipidemia Associated With Type II Diabetes Mellitus\|Statin Adverse Reaction\|Hypogonadism, Male\|Adrenal Insufficiency\|Vitamin D Deficiency	March 1, 2021	Phase 4
NCT02245087	University Health Network, Toronto	Coronary Artery Disease	August 2014	Phase 2
NCT01033058	Beijing Chao Yang Hospital\|Pfizer	STEMI	December 2009	Phase 4
NCT03275376	Taichung Veterans General Hospital	Overall Survival\|Tumor Responses	December 21, 2017	Phase 2
NCT00728013	Ministry of Science and Technology of the People´s Republic of China	Acute Coronary Syndrome	December 2006	Not Applicable
NCT03073863	Korea University Guro Hospital\|Pfizer	Cardiovascular Diseases	April 3, 1998	Phase 4
NCT03418974	Fudan University\|Peking University People´s Hospital\|Jiangsu Wanbang Medicine Marketing Co., Ltd.	Dyslipidemias	November 1, 2017	Phase 4
NCT01857921	Yonsei University	Coronary Artery	December 2010	Not Applicable
NCT02767362	UNC Lineberger Comprehensive Cancer Center\|Wilma Williams Education and Clinical Research for Endometrial Cancer Award	Endometrial Cancer	November 2015	Early Phase 1
NCT00654407	AstraZeneca	Hypercholesterolemia	November 2001	Phase 3
NCT01288443	Sanofi\|Regeneron Pharmaceuticals	Hypercholesterolemia	January 2011	Phase 2
NCT00689442	Akros Pharma Inc.	Dyslipidemia	January 2004	Phase 2
NCT02979704	Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh	Hyperlipidemia	September 2016	Phase 2\|Phase 3
NCT00965055	University of California, San Diego\|Merck Sharp & Dohme LLC	High Cholesterol\|Coronary Artery Disease	September 2009	Phase 3
NCT00136942	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Hyperlipidemia	April 2005	Phase 3
NCT02342015	University of Padova	Osteoporosis\|Hypercholesterolemia	November 2012	Phase 4
NCT00126048	University of Glasgow\|NHS Greater Glasgow and Clyde\|Asthma UK\|NHS Greater Clyde and Glasgow	Asthma	July 2005	Phase 2\|Phase 3
NCT05103644	Beni-Suef University	Breast Cancer	October 30, 2021	Phase 2\|Phase 3
NCT03247400	Nicolaus Copernicus University	Non-segmental Vitiligo	December 1, 2016	Phase 1\|Phase 2
NCT00590135	The Cleveland Clinic\|Pfizer	Aortic Valve Stenosis	August 2000	Phase 4
NCT05970679	Daewon Pharmaceutical Co., Ltd.	Hypercholesterolemia, Dyslipidemia	August 17, 2022	Phase 3
NCT03750760	Imperial College London\|Regeneron Pharmaceuticals\|Baim Institute for Clinical Research	Myocardial Infarction\|Dyslipidemias	January 2020	Phase 4
NCT05679102	Himayat Ullah\|Ayub Teaching Hospital\|Khyber Medical University Peshawar\|Shaqra University	Atorvastatin Antihypertensive Effect	December 20, 2022	Not Applicable
NCT02089061	Bristol-Myers Squibb	Acute Coronary Syndromes	March 2014	Phase 1
NCT01806324	HanAll BioPharma Co., Ltd.	Hypertension\|Hyperlipidemia	April 2012	Phase 1
NCT00690443	Aegerion Pharmaceuticals, Inc.	Hypercholesterolemia	May 2008	Phase 2
NCT01863225	Resverlogix Corp\|South Australian Health and Medical Research Institute	Dyslipidemia\|Coronary Artery Disease	May 2013	Phase 2
NCT02416427	Regina Elena Cancer Institute	Breast Neoplasms	May 2015	Phase 2
NCT00756886	University of Alabama at Birmingham\|Pfizer	Arrhythmia	September 2008	Not Applicable
NCT00166036	Emory University	Diabetes Mellitus\|Metabolic Syndrome X\|Hypercholesterolemia	September 2004	Phase 2
NCT01820767	Ricardo Mouzo Mirco\|Hospital El Bierzo	Chronic Kidney Disease	August 2012	Phase 3
NCT05507398	Tanta University	Breast Cancer Female	October 2022	Phase 4
NCT02608697	Catabasis Pharmaceuticals	Hypercholesterolemia	October 2015	Phase 2
NCT01974297	Sang Hak Lee\|Yonsei University	Mixed Hyperlipidemia	July 2013	Not Applicable
NCT05180942	Monash University\|National Health and Medical Research Council, Australia	Melanoma\|Atherosclerosis	November 7, 2022	Phase 2
NCT00862251	Organon and Co	Cardiovascular Disorder\|Diabetes Mellitus	April 2009	Phase 3
NCT01759836	Asan Medical Center\|Dong-A Pharmaceutical	Prostatic Neoplasms	October 2012	Phase 2
NCT03801733	Akebia Therapeutics	Drug Interaction Potentiation	June 17, 2018	Phase 1
NCT01448174	Poznan University of Medical Sciences	Renal Failure Chronic Requiring Hemodialysis\|Metabolic Syndrome\|Diabetes Mellitus Type 2\|Hyperlipidemia	October 2011	Phase 4
NCT02470455	Shri Ramachandra Bhanj Medical College	Prediabetic State	July 2011
NCT00344370	Kowa Research Europe	Type II Diabetes Mellitus\|Dyslipidemia	August 2006	Phase 3
NCT01697735	Wenzhou Medical University	Dyslipidemias	September 2012	Phase 4
NCT04767984	National Cancer Institute (NCI)	Colorectal Carcinoma\|Ulcerative Colitis	September 24, 2021	Phase 2
NCT03819101	Gustave Roussy, Cancer Campus, Grand Paris\|National Cancer Institute, France	Prostate Cancer	June 6, 2019	Phase 3
NCT04824911	Chang Gung Memorial Hospital	Acute Stroke\|Dual Antiplatelet Therapy\|Statin	March 23, 2021	Phase 2
NCT05792293	Ain Shams University	Doxorubicin Induced Cardiomyopathy	June 1, 2021	Phase 2\|Phase 3
NCT03906539	All India Institute of Medical Sciences, Bhubaneswar\|Coconut Development Board, Government of India	Dyslipidemias	May 22, 2019	Phase 4
NCT01218204	GlaxoSmithKline	Dyslipidaemias\|Dyslipidemias	September 14, 2010	Phase 2
NCT01733953	University of Minnesota	Cardiovascular Disease\|Childhood ALL\|Childhood NHL	November 2012	Phase 2
NCT00654225	AstraZeneca	Hypercholesterolemia\|Dyslipidaemia	October 2002	Phase 3
NCT01953328	Amgen	Hyperlipidemia or Mixed Dyslipidemia at High Risk for Cardiovascular Events	October 2013	Phase 3
NCT01491256	The Korean Society of Circulation	Acute Coronary Syndrome	February 2010	Not Applicable
NCT00804843	Merck Sharp & Dohme LLC	Carotid Atherosclerosis	April 2009	Phase 2
NCT00926614	Brooke Army Medical Center	Hepatitis c	September 2008	Phase 4
NCT00110435	Organon and Co	Type 2 Diabetes Mellitus\|Hypercholesterolemia	May 2005	Phase 3
NCT05306990	Helwan University	Hydroxymethylglutaryl-CoA Reductase Inhibitors\|Diabetes Mellitus	April 20, 2017	Not Applicable
NCT00395603	Organon and Co	Cardiovascular Diseases\|Diabetes Mellitus	September 2006	Phase 3
NCT00991705	Boryung Pharmaceutical Co., Ltd	Essential Hypertension	July 2009	Phase 1
NCT03176498	Sclnow Biotechnology Co., Ltd.	Cerebral Infarction	December 2023	Phase 1\|Phase 2
NCT00361283	University of Florida\|American Heart Association\|American College of Clinical Pharmacy	Inflammation	June 2004	Phase 4
NCT01214746	Regional Hospital Holstebro	Cardiovascular Diseases\|Nephropathy	May 2010	Phase 2
NCT03464682	Zhejiang Hisun Pharmaceutical Co. Ltd.	Primary Hypercholesterolemia	February 28, 2015	Phase 3
NCT02496962	Shi Yang\|Chinese PLA General Hospital	Sleep Deprivation	July 2015	Not Applicable
NCT05504330	Anhui Medical University	Asymptomatic Intracranial Stenosis\|Cognitive Impairment\|Cerebrovascular Event	August 15, 2022
NCT01023607	Harbin Medical University	Coronary Artery Disease\|Hyperlipidemia	December 2009	Phase 4
NCT01842256	Chong Kun Dang Pharmaceutical	Essential Hypertension\|Hyperlipidemia	April 2013	Phase 1
NCT00195793	Abbott	Hyperlipidemia	August 2004	Phase 3
NCT00296400	AstraZeneca	Hyperlipidemia	February 2006	Phase 2
NCT01041729	Hospital Universitario Getafe	Peripheral Arterial Disease	January 2008	Phase 4
NCT03532620	Jun Tao\|Sun Yat-sen University\|First Affiliated Hospital, Sun Yat-Sen University	Prediabetic State\|Hypertension\|Dyslipidemias	August 9, 2018	Phase 4
NCT00987974	Radboud University Medical Center	Ischemia Reperfusion Injury\|Endothelial Dysfunction	September 2009	Phase 4
NCT03867318	Organon and Co	Hypercholesterolemia	April 24, 2000	Phase 3
NCT05561062	Tanta University	Inflammatory Bowel Diseases	December 1, 2022	Phase 2
NCT02668016	Imperial College London	Adverse Effects\|Cardiovascular Diseases\|Hyperlipidemias	March 2016	Phase 4
NCT01335048	Ospedale Misericordia e Dolce	Stable Angina	April 2011	Phase 4
NCT04147286	University of Cape Town\|University of Zurich\|University of Namibia\|University of Bern\|University of Stellenbosch	Tuberculosis, Pulmonary	July 14, 2020	Phase 2\|Phase 3
NCT02726555	Wenzhou Medical University	Dyslipidemia\|Atherosclerosis	November 2015	Phase 3
NCT01058057	University Hospital, Motol	Coronary Artery Disease\|Coronary Angioplasty	February 2008	Phase 3
NCT01548326	Nematollah Jonaidi Jafari\|Baqiyatallah Medical Sciences University	Hepatitis B\|Vaccination Failure	September 2011	Phase 4
NCT03753555	General Hospital of Shenyang Military Region	Stroke, Ischemic\|Atherosclerosis, Cerebral	December 1, 2018	Phase 4
NCT01285544	Seoul National University Hospital\|Dong-A Pharmaceutical	Dyslipidemia\|Cardiovascular Disease\|Hypercholesterolemia	September 2008	Phase 4
NCT00154024	Technische Universität Dresden	Healthy Subjects	March 2003	Not Applicable
NCT01997294	Zhang Qi, MD\|Shanghai Jiao Tong University School of Medicine	Acute Myocardial Infarction	January 2013	Not Applicable
NCT01550419	Shanghai Minhang Central Hospital\|Shanghai Jiao Tong University School of Medicine	Ventilator-associated Pneumonia\|Ischemic Stroke	March 2012	Early Phase 1
NCT00666029	University Hospital Southampton NHS Foundation Trust	Metabolic Syndrome	February 2006	Phase 2
NCT01526460	IRCCS San Raffaele	Platelet Dysfunction	August 2011	Phase 2
NCT04591808	Institut de Recherches Internationales Servier\|ADIR, a Servier Group company\|Servier	Dyslipidemias\|Hypertension	September 9, 2021	Phase 3
NCT00286312	R&D Cardiologie\|UMC Utrecht	Myocardial Infarction\|Reperfusion Injury	February 2006	Phase 4
NCT00772564	Rambam Health Care Campus\|Pfizer	Myocardial Infarction	August 2008	Phase 4
NCT04850001	Anhui Medical University	Magnetic Resonance Imaging\|Asymptomatic Intracranial Stenosis\|Medical Treatment	September 10, 2020
NCT00120133	Children´s Mercy Hospital Kansas City	Osteoporosis	December 2004	Not Applicable
NCT02166593	Yooyoung Pharmaceutical Co., Ltd.	Combined Dyslipidemia	May 2014	Phase 3
NCT00549926	Yokohama City University Medical Center	Coronary Disease\|Hypercholesterolemia	October 2007	Phase 4
NCT02957162	University Hospitals of North Midlands NHS Trust	Acute Coronary Syndrome	March 2016	Phase 4
NCT00120055	University of Oslo School of Pharmacy	Myopathy	February 2005	Phase 4
NCT00367458	National Institute of Allergy and Infectious Diseases (NIAID)\|National Institutes of Health Clinical Center (CC)	HIV	October 18, 2006	Phase 2
NCT02550288	Organon and Co	Hypercholesterolemia	September 29, 2015	Phase 3
NCT02243098	Novo Nordisk A+S	Diabetes\|Healthy	September 16, 2014	Phase 1
NCT00309751	Kowa Research Europe	Type II Diabetes Mellitus\|Dyslipidemia	December 2005	Phase 3
NCT00392717	The University of Western Australia	Obesity\|Dyslipidemia\|Insulin Resistance	February 1998	Phase 3
NCT01732718	University of North Carolina, Chapel Hill\|National Heart, Lung, and Blood Institute (NHLBI)	Sickle Cell Disease\|Sickle Cell Nephropathy	September 2013	Phase 2
NCT04472637	Alexandria University	Arterial Stiffness	November 1, 2020	Phase 2
NCT01306565	Hormozgan University of Medical Sciences	Cardiovascular Disease	January 2009	Not Applicable
NCT01645423	Dr. Reddy´s Laboratories Limited	Healthy	August 2009	Phase 1
NCT00965185	Massachusetts General Hospital\|National Heart, Lung, and Blood Institute (NHLBI)	Cardiovascular Disease\|HIV\|Atherosclerosis\|Inflammation\|Statins, HMG-CoA\|HIV Infections	September 2009	Not Applicable
NCT00335504	National Cancer Institute (NCI)	Colon Cancer\|Precancerous Condition\|Rectal Cancer	March 2006	Phase 2
NCT05030818	Fundación para la Investigación Biosanitaria del Principado de Asturias	Coronary Artery Disease	October 14, 2022	Phase 4
NCT01547455	Peking Union Medical College\|Chinese Academy of Medical Sciences, Fuwai Hospital	Acute Kidney Injury	April 2012	Not Applicable
NCT04882293	Laboratorios Silanes S.A. de C.V.	Dyslipidemia Associated With Type II Diabetes Mellitus	February 15, 2022	Phase 3
NCT00990808	Merck Sharp & Dohme LLC	Dyslipidemia	November 2009	Phase 1
NCT00242944	Kyoto University\|Yamaguchi University Hospital\|Juntendo University\|Kyoto University Hospital	Coronary Disease\|Hypercholesterolemia	November 2005	Phase 4
NCT00827606	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Familial Hypercholesterolemia	March 2009	Phase 3
NCT00235950	AstraZeneca	Coronary Heart Disease	January 2004	Phase 4
NCT00572312	Medical University of Gdansk	Chronic Kidney Disease\|Proteinuria	February 2005	Not Applicable
NCT00000941	National Institute of Allergy and Infectious Diseases (NIAID)	HIV Infections		Phase 1
NCT00979758	Chinese Academy of Medical Sciences, Fuwai Hospital	Myocardial Infarction\|Stem Cell Transplantation\|Angioplasty, Transluminal, Percutaneous Coronary	January 2009	Phase 2
NCT00134173	Pfizer	Coronary Disease\|Coronary Arteriosclerosis\|Hyperlipidemia	October 2003	Phase 3
NCT02910778	Medical University of Vienna	Ischemia	October 2016	Phase 4
NCT01946815	Keimyung University Dongsan Medical Center\|Seoul National University Hospital\|Ulsan University Hospital\|Inje University Ilsan Paik Hospital	Coronary Artery Disease	September 2013	Phase 3
NCT00917527	Yonsei University	Coronary Heart Disease	June 2009	Phase 4
NCT00412841	NYU Langone Health	Avascular Necrosis	November 2002	Phase 2
NCT01528709	Boca Raton Regional Hospital\|Pfizer	Saphenous Vein Graft Disease	March 2012	Phase 3
NCT00469326	University Hospital, Motol	Coronary Artery Disease	April 2005	Phase 3
NCT00751907	University of Wisconsin, Madison\|National Institute on Aging (NIA)	Alzheimer´s Disease	June 2006	Phase 2
NCT04984616	Juan D. Maya\|University of Chile	Chronic Chagas Disease	October 12, 2021	Phase 2
NCT00669695	University Hospital, Grenoble	Obstructive Sleep Apnea Syndrome	May 2008	Phase 2
NCT01105975	Eli Lilly and Company	Dyslipidemia	April 2010	Phase 2
NCT01761656	Central South University	Stable Angina\|Unstable Angina\|Acute Non-ST-segment Elevation Myocardial Infarction	December 2012	Phase 2
NCT03051100	Esperion Therapeutics, Inc.	Hypercholesterolemia	January 19, 2017	Phase 2
NCT00454545	Skane University Hospital	Crohns Disease	October 2006	Phase 2
NCT05839236	Yang I. Pachankis\|Pachankis, Yang I., M.D.	COVID-19 Stress Syndrome\|COVID-19 Vaccine Adverse Reaction\|COVID-19-Associated Thromboembolism\|COVID-19 Post-Intensive Care Syndrome\|COVID-19-Associated Stroke\|COVID-19 Respiratory Infection	May 1, 2023	Phase 1
NCT02364258	Children´s Mercy Hospital Kansas City	Dyslipidemia	July 2014	Phase 1
NCT04863274	The League of Clinical Research, Russia\|National Research Center for Preventive Medicine	Lipid Metabolism Disorders	June 21, 2018
NCT04056039	Hospital Central Dr. Ignacio Morones Prieto	Cardiovascular Diseases\|Arthritis, Rheumatoid	August 14, 2018	Phase 2
NCT05730634	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	Diabetes Mellitus, Type 2\|Vascular Inflammation	June 1, 2019	Not Applicable
NCT00973271	Essentialis, Inc.	Hypertriglyceridemia	March 2011	Phase 3
NCT01363999	Hoffmann-La Roche	Healthy Volunteer	June 2011	Phase 1
NCT00587379	Mayo Clinic\|Pfizer	Endothelial Dysfunction	June 2004	Not Applicable
NCT03461081	Jeil Pharmaceutical Co., Ltd.	Hypertension With Hyperlipidemia	May 7, 2017	Phase 1
NCT02685462	Tobira Therapeutics, Inc.	Healthy	January 31, 2016	Phase 1
NCT02706860	Cairo University	Coronary Artery Bypass Grafting	June 2013	Phase 4
NCT02386033	Government Dental College and Research Institute, Bangalore	Chronic Periodontitis	November 2013	Phase 2\|Phase 3
NCT01763866	Amgen	Hyperlipidemia	January 15, 2013	Phase 3
NCT03072082	Jun Li\|China Academy of Chinese Medical Sciences\|Guang´anmen Hospital of China Academy of Chinese Medical Sciences	Coronary Artery Disease(CAD)	June 2017	Phase 4
NCT02066207	Chong Kun Dang Pharmaceutical	Dyslipidemia (Fredrickson Type ?a)\|Dyslipidemia (Fredrickson Type ?b)	March 18, 2014	Phase 1
NCT01984424	Amgen	Hyperlipidemia	December 10, 2013	Phase 3
NCT03872388	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Anatomic Stage IIB Breast Cancer AJCC v8\|Anatomic Stage III Breast Cancer AJCC v8\|Anatomic Stage IIIA Breast Cancer AJCC v8\|Anatomic Stage IIIB Breast Cancer AJCC v8\|Anatomic Stage IIIC Breast Cancer AJCC v8\|Estrogen Receptor Negative\|HER2+Neu Negative\|Inflammatory Breast Carcinoma\|Progesterone Receptor Negative\|Prognostic Stage IIB Breast Cancer AJCC v8\|Prognostic Stage III Breast Cancer AJCC v8\|Prognostic Stage IIIA Breast Cancer AJCC v8\|Prognostic Stage IIIB Breast Cancer AJCC v8\|Prognostic Stage IIIC Breast Cancer AJCC v8\|Stage IIB Breast Cancer AJCC v6 and v7\|Stage III Breast Cancer AJCC v7\|Stage IIIA Breast Cancer AJCC v7\|Stage IIIB Breast Cancer AJCC v7\|Stage IIIC Breast Cancer AJCC v7\|Triple-Negative Breast Carcinoma	January 14, 2019	Phase 2
NCT00942591	Insel Gruppe AG, University Hospital Bern\|PharmaPart\|Laboratory: Viollier AG Spalenring 145 + 147 Postfach 4002 Basel	Multiple Sclerosis	May 2005	Phase 2
NCT00252967	Emory University\|Pfizer	Atrial Fibrillation\|Inflammation	October 2005	Phase 3
NCT00734123	Hospital Arnau de Vilanova\|Pfizer	Atherosclerosis\|Cardiovascular Diseases	April 2008	Phase 4
NCT05826912	University of California, San Francisco\|United States Department of Defense	Traumatic Brain Injury	August 30, 2023	Phase 2
NCT00616187	Charite University, Berlin, Germany\|German Research Foundation\|German Federal Ministry of Education and Research\|Pfizer	Relapsing Remitting Multiple Sclerosis	October 2003	Phase 2
NCT05675787	Peking University People´s Hospital	Atypical Endometrial Hyperplasia\|Endometrial Carcinoma Stage I	January 6, 2023	Phase 2
NCT04375787	Mohamed Abdelfatah\|Assiut University	Coronary Disease	March 15, 2020	Phase 4
NCT01448642	Hospital do Coracao\|Ministry of Health, Brazil	Acute Coronary Syndrome	April 2012	Phase 4
NCT00359281	Aegerion Pharmaceuticals, Inc.	Healthy	March 2006	Phase 2
NCT01929135	Universidad de los Andes, Chile\|Corporación de Fomento de la Producción, Chile	Chronic Periodontitis	May 2013	Phase 2
NCT00163202	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|MDS Pharma Services\|Bio-Inova Life Sciences International\|Pfizer	Coronary Arteriosclerosis\|Hypercholesterolemia	June 2002	Phase 4
NCT01299181	University of Edinburgh\|NHS Lothian	Bronchiectasis	November 2010	Phase 4
NCT02189837	Amgen	Primary Hyperlipidemia and Mixed Dyslipidemia	July 8, 2014	Phase 3
NCT00723320	Ministry of Science and Technology of the People´s Republic of China\|Peking University First Hospital	Atherosclerosis	February 2008	Not Applicable
NCT03482180	Kuhnil Pharmaceutical Co., Ltd.	Dyslipidemias	May 4, 2016	Phase 3
NCT01257009	UMC Utrecht	Stable Chronic Kidney Disease\|Hypertension	August 2009	Phase 4
NCT02994745	Boryung Pharmaceutical Co., Ltd	Hypertension, Hyperlipidemia	December 23, 2016	Phase 1
NCT00517257	University of Toronto\|Unity Health Toronto\|Pfizer\|Canadian Heart Research Centre\|Ontario Association of Optometrists\|Toronto Ophthalmological Society	Retinal Vein Occlusion\|Retinal Vein Thrombosis\|Central Retinal Vein Occlusion\|Branch Retinal Vein Occlusion\|Thrombosis	August 2007	Phase 3
NCT00651378	Organon and Co\|Merck Sharp & Dohme LLC	Hypercholesterolemia\|Atherosclerosis\|Coronary Artery Disease	September 1, 2004	Phase 4
NCT00793754	Fundacion GESICA	Diabetes Mellitus	March 2009	Phase 4
NCT02586155	Resverlogix Corp\|PPD\|ICON plc\|Medidata Solutions	Diabetes Mellitus, Type 2\|Coronary Artery Disease	November 2015	Phase 3
NCT03867110	Organon and Co	Hypercholesterolemia	March 6, 2000	Phase 3
NCT00675779	Poznan University of Medical Sciences\|University of California, Davis\|Biomet Polska Sp. z.o.o.	Endometriosis\|Pain	April 2008	Not Applicable
NCT02863185	Dong-A University	Chronic Kidney Disease	May 1, 2016	Phase 4
NCT00902967	B. J. Medical College, Pune	Abdominal Surgery	July 2009	Phase 3
NCT00644670	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Dyslipidemias	June 2003	Phase 4
NCT01166633	JW Pharmaceutical	Hypercholesterolemia	June 2009	Phase 4
NCT02633956	Intercept Pharmaceuticals	Nonalcoholic Steatohepatitis	December 4, 2015	Phase 2
NCT04379999	Fox Chase Cancer Center	Lynch Syndrome	September 10, 2018	Early Phase 1
NCT01572623	Campus Bio-Medico University	Carotid Stenosis	July 2011	Phase 4
NCT02093390	Millennium Pharmaceuticals, Inc.	Prostate Cancer\|Endometriosis	March 2014	Phase 1
NCT01050348	The Western Pennsylvania Hospital\|West Penn Allegheny Health System	Acute Myocardial Infarction	June 2009	Phase 4
NCT00243672	University Hospital Muenster	Atherosclerosis	October 2005	Phase 4
NCT00120887	Johns Hopkins University\|Lupus Research Alliance	Systemic Lupus Erythematosus	April 2002	Phase 4
NCT00496730	Organon and Co	Hypercholesterolemia	July 2007	Phase 3
NCT04608344	Gilead Sciences\|Galapagos NV	Rheumatoid Arthritis	November 4, 2020	Phase 1
NCT00134485	Pfizer	Hypercholesterolemia, Familial\|Hyperlipidemia	March 2005	Phase 3
NCT04801940	Cambridge University Hospitals NHS Foundation Trust\|University of Liverpool\|Cambridge University Hospitals NHS Foundation Trust (joint Sponsor)\|The University of Cambridge (joint Sponsor)	Covid19	May 19, 2021	Phase 3
NCT00967434	Ottawa Hospital Research Institute\|Canadian Anesthesiologists´ Society\|Heart and Stroke Foundation of Ontario	Inflammation\|Myocardial Infarction\|Myocardial Ischemia	December 2007	Not Applicable
NCT01322711	University of Roma La Sapienza	Type 2 Diabetes Mellitus\|Hypercholesterolemia	March 2011	Phase 4
NCT00920101	National Defense Medical College, Japan	Atherosclerosis\|Inflammation	June 2009	Phase 4
NCT00327691	Pfizer	Cardiovascular Disease\|Cerebrovascular Accident\|Coronary Heart Disease	April 1998	Phase 4
NCT01372839	Xijing Hospital	Myocardial Infarction\|Unstable Angina	July 2010	Phase 4
NCT00687271	Merck Sharp & Dohme LLC	Hypercholesterolemia	June 14, 2008	Phase 2
NCT01780948	Chulalongkorn University\|Ratchadapiseksompotch Research Fund	Difference of 12-hour AUC	September 2012	Not Applicable
NCT02192320	Oriental Neurosurgery Evidence-Based-Study Team	Chronic Subdural Hematoma	July 2014	Phase 2
NCT01503671	National Taiwan University Hospital	Heart Failure	November 2011	Phase 4
NCT00134498	Pfizer	Hypertriglyceridemia\|Hyperlipoproteinemia Type IV	February 2005	Phase 3
NCT00153166	Brigham and Women´s Hospital\|National Heart, Lung, and Blood Institute (NHLBI)	Arterial Occlusive Disease\|Intermittent Claudication\|Insulin Resistance	January 2004	Phase 2\|Phase 3
NCT02503865	Nazarbayev University\|Institute Of Cardiology & Internal Diseases, Kazakhstan	Metabolic Syndrome	January 2003	Phase 1\|Phase 2
NCT01495013	GlaxoSmithKline	Diabetes Mellitus, Type 2	December 2011	Phase 3
NCT00541697	Organon and Co	Diabetes Mellitus, Type 2	January 19, 2005	Phase 3
NCT01870804	Centro Cardiopatici Toscani	Acute Coronary Syndrome	May 2013	Phase 4
NCT04262765	Midas Pharma GmbH	Healthy Volunteers	February 23, 2019	Phase 1
NCT01665677	Mehdi Hamadani\|West Virginia University\|Medical College of Wisconsin	Graft vs Host Disease	January 20, 2014	Phase 2
NCT04666389	I.M. Sechenov First Moscow State Medical University	Contrast-induced Acute Kidney Injury\|Cardiovascular Diseases	October 15, 2020	Not Applicable
NCT04262206	Duke University\|National Institute on Aging (NIA)\|National Heart, Lung, and Blood Institute (NHLBI)\|Wake Forest University Health Sciences	Cognitive Impairment, Mild\|Dementia\|Cardiovascular Diseases	September 1, 2020	Phase 4
NCT00665834	Queen´s University\|AstraZeneca	Dyslipidemia\|Acute Coronary Syndromes	April 2006	Phase 4
NCT05331053	Penn State University	Endometriosis	May 1, 2018	Phase 4
NCT04754789	Assiut University	ST Elevation Myocardial Infarction	February 20, 2021	Phase 3
NCT02662569	Amgen	Diabetes, Hyperlipidemia, Mixed Dyslipidemia	April 14, 2016	Phase 3
NCT01394848	Yonsei University\|OrbusNeich\|Yuhan Corporation	Stable Angina	October 2011	Phase 4
NCT05250596	Azienda USL Toscana Centro	Non ST Segment Elevation Acute Coronary Syndrome	February 24, 2022	Phase 2
NCT01617538	Capital Medical University	Stenosis	January 2012	Phase 1\|Phase 2
NCT00157924	Organon and Co	Hypercholesterolemia	November 2005	Phase 4
NCT03072121	Jun Li\|Shanghai Hutchison Pharmaceuticals Limited\|Guang´anmen Hospital of China Academy of Chinese Medical Sciences	Coronary Artery Disease(CAD)	June 2017	Phase 4
NCT00442325	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Coronary Arteriosclerosis\|Diabetes Mellitus, Type 2\|Cerebrovascular Accident\|Dyslipidemia\|Peripheral Vascular Disease	January 2003	Phase 4
NCT03885921	Organon and Co	Hypercholesterolemia	October 25, 2000	Phase 3
NCT03956368	Chinese University of Hong Kong	Chronic Subdural Hematoma	January 9, 2020	Phase 3
NCT00632840	The University of Western Australia\|National Heart Foundation, Australia	Obesity\|Lipid Disorders\|Hypertriglyceridemia\|Cardiovascular Disease	June 2001	Phase 4
NCT03188978	Albany Medical College	Primary Arteriovenous Fistula Failure	November 1, 2018	Phase 1\|Phase 2
NCT02185066	HK inno.N Corporation	Healthy Volunteers	July 2014	Phase 1
NCT00151502	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Alzheimer´s Disease	November 2002	Phase 3
NCT04765137	Johns Hopkins University	Mild Cognitive Impairment	May 21, 2021	Phase 2
NCT00491400	Boston University	Diabetes Mellitus\|Metabolic Syndrome	September 2005	Not Applicable
NCT00437892	Università degli Studi dell´Insubria	Venous Thromboembolism\|Hypercholesterolemia	May 2007	Phase 2
NCT03004001	Gloria Vega\|Regeneron Pharmaceuticals\|Aventis Pharmaceuticals\|Dallas VA Medical Center	Nephrotic Syndrome	January 2017	Phase 2
NCT01518166	Novo Nordisk A+S	Diabetes\|Healthy	May 2006	Phase 1
NCT02591836	NeuroBo Pharmaceuticals Inc.	Hypercholesterolemia	January 2003	Phase 2
NCT02099123	Monash University\|National Health and Medical Research Council, Australia\|National Heart Foundation, Australia	Independent Living\|Disability Free Survival\|Elderly\|Healthy	July 2015	Phase 4
NCT04486508	Rajaie Cardiovascular Medical and Research Center\|Brigham and Women´s Hospital\|Tehran Heart Center\|Masih Daneshvari Hospital\|Hazrat Rasool Hospital\|Modarres Hospital\|Firuzgar hospital affiliated to Iran University of Medical Sciences\|Imam Khomeini Hospital\|Sina Hospital, Iran\|Tabriz University of Medical Sciences\|Shariati Hospital\|Imam Ali Hospital\|Labbafinejhad Hospital	Covid19	July 30, 2020	Phase 3
NCT02764736	Albert Einstein Healthcare Network	Complication of Renal Dialysis	March 4, 2016	Not Applicable
NCT02455869	Government Dental College and Research Institute, Bangalore	Chronic Periodontitis	July 2014	Phase 2\|Phase 3
NCT05589454	Sichuan Provincial People´s Hospital\|Science & Technology Department of Sichuan Province	Acute Ischemic Stroke\|Cerebral Microbleeds	January 2023	Phase 4
NCT00610545	University of Campinas, Brazil	Vascular Surgery	July 2007	Phase 4
NCT01499771	Ranbaxy Laboratories Limited\|Ranbaxy Inc.	Healthy	October 2009	Phase 1
NCT02714569	Eli Lilly and Company	Dyslipidemias	March 2016	Phase 1
NCT04904536	The George Institute\|University of Sydney\|Monash University\|The Alfred\|Universidad del Desarrollo	Neurocognitive Impairment, Mild	March 10, 2022	Phase 3
NCT01497912	Karolinska Institutet	Type 1 Diabetes Mellitus\|Dyslipidemia	January 2005	Phase 4
NCT01779453	Esperion Therapeutics, Inc.	Hypercholesterolemia	December 2012	Phase 2
NCT00233480	University of California, Los Angeles\|Pfizer\|National Heart, Lung, and Blood Institute (NHLBI)	Heart Failure, Congestive	August 2005	Phase 4
NCT03122639	Columbia University\|National Heart, Lung, and Blood Institute (NHLBI)	Obstructive Sleep Apnea of Adult	September 1, 2017	Early Phase 1
NCT03047772	Yuejin Yang\|Peking Union Medical College Hospital\|The First Hospital of Hebei Medical University\|Zunyi Medical College\|Chinese Academy of Medical Sciences, Fuwai Hospital	Myocardial Infarction\|Stem Cell Transplantation\|Angioplasty, Transluminal, Percutaneous Coronary	March 6, 2018	Phase 2
NCT04101136	Dr Cipto Mangunkusumo General Hospital	CMV	September 30, 2019	Not Applicable
NCT00739999	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Pediatric Heterozygous Hypercholesterolemia	December 2008	Phase 1
NCT04026230	Tampere University Hospital\|Turku University Hospital\|Central Finland Hospital District\|Tartu University Hospital\|University of Aarhus\|Fimlab laboratories\|Helsinki University Central Hospital\|Kuopio University Hospital\|Oulu University Hospital\|Seinajoki Central Hospital\|The Hospital of Vestfold\|Telemark Hospital Trust	Metastatic Prostate Cancer\|Recurrent Prostate Cancer	August 15, 2019	Phase 3
NCT04661709	Guang´anmen Hospital of China Academy of Chinese Medical Sciences\|Special Project of National Traditional Chinese Medicine Clinical Research Base of State Administration of Traditional Chinese Medicine\|National Natural Science Foundation of China	Coronary Heart Disease\|Unstable Angina\|Chinese Herbal Medicine	March 1, 2021	Phase 4
NCT00654485	AstraZeneca	Metabolic Syndrome	May 2002	Phase 3
NCT01431105	University of California, San Diego\|Children´s Hospital Colorado\|University of Colorado, Denver	Kawasaki Disease	July 2012	Phase 1\|Phase 2
NCT01648829	University of Roma La Sapienza	Coronary Artery Disease	January 2014	Phase 4
NCT01186289	Duke University\|Pfizer	Neurocognitive Dysfunction	October 2010	Not Applicable
NCT00536887	Korea University Anam Hospital	Acute Myocardial Infarction	July 2005	Phase 4
NCT00844376	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Hypercholesterolemia	February 2008	Phase 4
NCT00644709	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Dyslipidemias	September 2003	Phase 4
NCT00449410	Radboud University Medical Center\|Pfizer\|Schering-Plough	Atrial Fibrillation\|Neuropsychology\|Magnetic Resonance Imaging\|Inflammation\|Hemostasis	May 2005	Phase 4
NCT03696940	Laboratorios Grossman, S.A.\|Instituto Nacional de Salud Publica, Mexico	Dyslipidemias\|Cardiovascular Risk Factor	May 28, 2018	Phase 3
NCT01228227	Gennaro Sardella\|University of Roma La Sapienza	Assess the Periprocedural Myocardial Necrosis	October 2010	Phase 3
NCT00910221	Austin Health	Acute Kidney Dysfunction	March 2008	Phase 2\|Phase 3
NCT00911339	IRCCS Policlinico S. Matteo	Stable Coronary Artery Disease	January 2009	Phase 3
NCT04601116	Aarhus University Hospital\|Rigshospitalet, Denmark\|Hospital of Southern Jutland\|University of Copenhagen\|Bornholms Hospital\|Naestved Hospital\|Vejle Hospital\|Odense University Hospital\|Nordsjaellands Hospital\|Aalborg University Hospital\|Herning Hospital	Breast Cancer Female\|Estrogen Receptor Positive Tumor	January 4, 2021	Phase 3
NCT01987310	Sheba Medical Center	Non Alcoholic Fatty Liver Disease	December 2015	Not Applicable
NCT00616772	AbbVie (prior sponsor, Abbott)\|AbbVie	Coronary Artery Disease\|Coronary Heart Disease\|Dyslipidemia	February 2008	Phase 3
NCT00300469	Abbott	Mixed Dyslipidemia\|Coronary Heart Disease\|Dyslipidemia	March 2006	Phase 3
NCT02497638	University Health Network, Toronto	Prostate Cancer	December 2021	Phase 2
NCT05464628	Gannex Pharma Co., Ltd.	Healthy	August 8, 2022	Phase 1
NCT04251364	Centre d´Expertise sur l´Altitude EXALT	Hypoxia, Altitude	February 15, 2020	Not Applicable
NCT00681525	Abbott	Pharmacokinetics	April 2008	Phase 1
NCT00645151	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Dyslipidemias	April 2004	Phase 4
NCT05093205	Pfizer	Healthy Adults	October 25, 2021	Phase 1
NCT00808717	Yonsei University	Myocardial Infarction\|Angioplasty\|Percutaneous Coronary	July 2007	Phase 4
NCT01250834	Eli Lilly and Company	Healthy Volunteers	December 2010	Phase 1
NCT00481364	Ercan OK\|Pfizer\|Ege University	Vascular Calcification\|Atherosclerosis\|Dyslipidemia\|Inflammation	November 2006	Phase 3
NCT02022293	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Nasopharyngeal Carcinoma\|Radiation Therapy Complication	January 2017	Phase 2
NCT00844402	Medical University of Graz	Primary Biliary Cirrhosis\|Hypercholesterolemia	January 2006	Phase 3
NCT00403533	Massachusetts General Hospital	Hepatitis C	February 2006	Phase 2
NCT00917644	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Hypercholesterolemia	July 2008	Phase 4
NCT01812707	Sanofi\|Regeneron Pharmaceuticals	Hypercholesterolemia	March 2013	Phase 2
NCT00427960	AstraZeneca	Hypercholesterolaemia	December 2006	Phase 4
NCT00150371	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Hypercholesterolemia	June 2004	Phase 3
NCT01956201	Chong Kun Dang Pharmaceutical	Mixed Hyperlipidemia	December 2013	Phase 3
NCT01525407	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Malignant Neoplasm	May 2012	Phase 2
NCT00409773	Organon and Co	Hypercholesterolemia\|Metabolic Syndrome	January 2007	Phase 3
NCT02850081	Columbia University	Carotid Artery Stenosis\|Strokes	June 1, 2017	Phase 3
NCT00576576	Emory University\|Pfizer	Atherosclerosis	July 2007	Not Applicable
NCT03874156	Vestre Viken Hospital Trust\|The Hospital of Vestfold\|Oslo University Hospital\|University of Oslo	Statin Adverse Reaction	March 5, 2019	Phase 4
NCT03031119	Pfizer	Healthy Volunteers	January 2017	Phase 1
NCT02603328	University of Chicago\|Johns Hopkins University	Cerebral Cavernous Malformation	July 17, 2018	Phase 1\|Phase 2
NCT01213498	Erling Bjerregaard Pedersen\|Regional Hospital Holstebro	Nephropathy\|Cardiovascular Diseases	May 2010	Phase 2
NCT00138762	Pfizer	Hyperlipidemia	July 2004	Phase 3
NCT00141141	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Hypercholesterolemia	January 2004	Phase 4
NCT03560882	Joaquina Baranda\|University of Kansas Medical Center	Malignant Disease\|Solid Tumor\|Acute Myeloid Leukemia\|Myelodysplastic Syndromes\|Cancer\|Relapsed Hematologic Malignancy	July 19, 2018	Phase 1
NCT02094313	University Hospital, Clermont-Ferrand\|Service de Biologie de la Reproduction : AMP-CECOS\|EA 975, Laboratoire de BDR\|Service d´Endocrinologie, Diabète et Maladies Métaboliques\|Laboratoire d´Hormonologie - Biochimie	Healthy Volunteers\|Normocholesterolaemic Men\|Normozoospermic Men	January 2008	Phase 1
NCT00092690	Organon and Co	Hypercholesterolemia	June 2003	Phase 3
NCT05764317	Servier Russia	Arterial Hypertension\|HTN	April 30, 2023
NCT00024531	Institute for the Study of Aging (ISOA)\|Pfizer\|National Institute on Aging (NIA)	Alzheimer Disease	October 2000	Phase 2
NCT00631189	AstraZeneca	Type IIa and IIb Hypercholesterolaemia	October 2007	Phase 4
NCT01624207	Seoul National University Hospital\|Yuhan corp., Seoul, Korea	Hypercholesterolemia	March 2010	Phase 4
NCT05511766	Tanta University	Cirrhosis\|Hepatic Encephalopathy\|Ascites\|Varices\|SBP - Spontaneous Bacterial Peritonitis	November 15, 2022	Phase 2\|Phase 3
NCT00276133	Yokohama City University Medical Center	Chronic Nephropathy	January 2004	Phase 4
NCT00770796	Ospedale Misericordia e Dolce	Contrast Induced Nephropathy	April 2006	Phase 4
NCT01386853	Tai Tien Pharmaceuticals Co., Ltd.	Hyperlipidemia	July 2011	Phase 3
NCT00818103	Sun Yat-sen University\|Third Affiliated Hospital, Sun Yat-Sen University	Multiple Sclerosis	January 2006	Not Applicable
NCT01013870	Baylor College of Medicine\|The University of Texas Health Science Center, Houston	Traumatic Brain Injury\|Post-traumatic Stress Disorder	February 2010	Phase 2
NCT01096875	Ankara University\|Turkish Society of Hematology	Coronary Artery Bypass Surgery\|Elective Surgical Procedure	February 2010	Phase 4
NCT05641753	NYU Langone Health\|National Heart, Lung, and Blood Institute (NHLBI)	Type 1 Diabetes	December 6, 2022	Phase 4
NCT04181749	University of Leicester\|University of Oxford\|British Heart Foundation\|National Institute for Health Research, United Kingdom	Cardiovascular Risk Factor	November 18, 2020	Phase 2
NCT00441597	Radboud University Medical Center\|Pfizer	Ischemia Reperfusion Injury\|Cardiovascular Disease	February 2007	Phase 4
NCT02097589	University of Florida	Healthy Controls	June 2014	Phase 1
NCT01200056	Prof. Stephen Lee\|Queen Mary Hospital, Hong Kong\|Pfizer\|The University of Hong Kong	Coronary Disease\|Ultrasonography, Interventional\|Hydroxymethylglutaryl-CoA Reductase Inhibitors	August 2007	Phase 4
NCT04915183	National Institute on Deafness and Other Communication Disorders (NIDCD)\|National Institutes of Health Clinical Center (CC)	Hearing Loss\|Head and Neck Cancer	August 27, 2023	Phase 3
NCT01477853	Merck Sharp & Dohme LLC	Type 2 Diabetes Mellitus	October 24, 2011	Phase 3
NCT04735263	Massachusetts Eye and Ear Infirmary	Age-related Macular Degeneration	February 4, 2021	Phase 2
NCT02056340	Beth Israel Deaconess Medical Center\|National Institute of General Medical Sciences (NIGMS)	Influenza	October 2013	Phase 2
NCT01073800	University of Alberta	Myocardial Infarction\|Stroke\|Renal Failure	April 2009	Phase 2\|Phase 3
NCT05741086	The First Affiliated Hospital with Nanjing Medical University	Stroke Patients With Symptomatic Intracranial Atherosclerotic Stenosis	April 15, 2023	Phase 3
NCT00249249	Kowa Research Europe	Primary Hypercholesterolemia\|Dyslipidemia	October 2005	Phase 3
NCT04072601	Copenhagen University Hospital, Hvidovre\|University of Copenhagen\|Aarhus University Hospital\|Rigshospitalet, Denmark	Liver Cirrhoses	November 8, 2019	Phase 4
NCT01557075	Yonsei University	Drug-eluting Stent (DES)	July 2010	Phase 4
NCT02800902	Government Dental College and Research Institute, Bangalore	Chronic Periodontitis	May 2015	Phase 2\|Phase 3
NCT00127335	Scripps Health	Myopathic Conditions	August 2005	Phase 4
NCT01053065	University of Padova\|Biomedical Foundation for Cardiovascular Research of Padova\|Pfizer	Symptomatic Carotid Stenosis\|Hypercholesterolemia\|Indication for Carotid Endarterectomy		Not Applicable
NCT03255044	Ain Shams University	Heart Failure	June 15, 2017	Phase 4
NCT03867994	rabab ahmed mohamed\|Cairo University\|October 6 University	Contrast-induced Nephropathy	February 1, 2016	Phase 2
NCT02374047	Catabasis Pharmaceuticals	Hypercholesterolemia	January 2015	Phase 1
NCT02350959	National Health Insurance Service Ilsan Hospital	Plaque	January 2015	Phase 4
NCT01689623	Janssen Research & Development, LLC	Healthy Participants	June 2012	Phase 1
NCT01255852	Jinling Hospital, China	CVD	January 2011	Phase 4
NCT02781064	London School of Hygiene and Tropical Medicine\|National Institute for Health Research, United Kingdom	Cardiovascular Disease	September 1, 2016	Phase 4
NCT02331095	Ohio State University	Venous Thromboembolism	January 2015	Early Phase 1
NCT01029522	Chong Kun Dang Pharmaceutical	Dyslipidemia	August 2008	Phase 4
NCT03837925	French Cardiology Society\|Fondation Coeur et Recherche\|ICAN Nutrition Education and Research\|Fédération francaise de cardiologie	Cardiovascular Diseases	June 13, 2019	Phase 3
NCT00777517	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Hypercholesterolemia	November 2008	Phase 1
NCT02355704	Instituto Mexicano del Seguro Social	Renal Insufficiency	January 2012	Phase 3
NCT02940366	Seoul National University Hospital\|JW Pharmaceutical	Metabolic Syndrome	December 1, 2016	Phase 4
NCT05946122	Minia University	Renal Protection	May 30, 2023	Phase 1
NCT00758004	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Hypercholesterolemia	October 2008	Phase 1
NCT04922424	Yale University	Hypertension\|Hyperlipidemias	September 30, 2022	Phase 1
NCT05483894	Samsung Medical Center	Hepatitis B\|Portal Hypertension	August 1, 2022	Phase 2
NCT05642845	Pharmtechnology LLC\|ClinPharmInvest, LLC	Bioequivalence	November 11, 2022	Phase 1
NCT00636766	Aristotle University Of Thessaloniki	Carotid Atherosclerosis\|Stroke\|Type 2 Diabetes\|Metabolic Syndrome	September 2005	Not Applicable
NCT05238012	Heart Health Research Center\|AstraZeneca	Metabolism Disorder, Lipid\|Metabolism Disorder, Glucose	July 1, 2022	Phase 4
NCT03414840	Yonsei University\|Chong Kun Dang Pharmaceutical Corp.	Coronary Artery Disease\|Hydroxymethylglutaryl-CoA Reductase Inhibitors\|Coronary Arteriosclerosis	April 1, 2018
NCT04151355	Ain Shams University\|Nasser Institute For Research and Treatment	Colorectal Cancer	October 1, 2019	Not Applicable
NCT02577042	Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia	Aging-related Inflammation in HIV-infected Patients	October 15, 2015	Phase 4
NCT01442428	University of Minnesota\|Pfizer\|Minnesota Medical Foundation	Immune Reconstitution Inflammatory Syndrome\|Immune Reconstitution Syndrome\|Tuberculosis\|HIV-infection+Aids	January 2014	Phase 2\|Phase 3
NCT00683618	AstraZeneca	Hypercholesterolemia	May 2008	Phase 3
NCT02024373	Oriental Neurosurgery Evidence-Based-Study Team	Chronic Subdural Hematoma	December 2013	Phase 2
NCT02958852	Lund University Hospital\|South Sweden Breast Cancer Group	Breast Cancer	November 2016	Phase 2
NCT03884452	Organon and Co	Familial Hypercholesterolemia	May 3, 2000	Phase 3
NCT00960323	Mutual Pharmaceutical Company, Inc.	Healthy	February 2009	Phase 1
NCT02452502	Second Affiliated Hospital, School of Medicine, Zhejiang University\|The First Hospital of Jilin University	Stroke	September 2, 2015	Not Applicable
NCT01770210	Elpen Pharmaceutical Co. Inc.	Cardiovascular Disorders	February 2013
NCT05815680	Innovent Biologics (Suzhou) Co. Ltd.	Overweight Subjects\|Obese Subjects	April 6, 2023	Phase 1
NCT00134550	Asker & Baerum Hospital\|Pfizer	Foot Ulcer\|Diabetes	February 2005	Phase 2
NCT02437084	Stanford University\|Doris Duke Charitable Foundation	Hyperlipidemia\|Insulin Resistance\|Type 2 Diabetes	May 2015	Phase 4
NCT00296387	AstraZeneca	Acute Coronary Syndrome	January 2006	Phase 3
NCT00355251	Germans Trias i Pujol Hospital\|Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia	HIV Infections	July 2006	Phase 4
NCT01555632	University of Nebraska\|National Cancer Institute (NCI)	Recurrent Prostate Cancer\|Stage I Prostate Cancer\|Stage IIA Prostate Cancer\|Stage IIB Prostate Cancer\|Stage III Prostate Cancer\|Stage IV Prostate Cancer	March 2012	Not Applicable
NCT01645449	Dr. Reddy´s Laboratories Limited	Healthy	June 2010	Phase 1
NCT00889226	JW Pharmaceutical	Hypercholesterolemia With Type2DM	April 2008	Phase 4
NCT05289063	Columbia University\|National Heart, Lung, and Blood Institute (NHLBI)	Obstructive Sleep Apnea of Adult	October 3, 2022	Phase 1
NCT00143741	University of Chicago	End-Stage Kidney Disease	May 2005	Phase 1
NCT00145431	Pfizer	Hyperlipoproteinemia Type III	March 2005	Phase 3
NCT02197065	Hospital for Special Surgery, New York\|Weill Medical College of Cornell University\|Washington University School of Medicine\|University of Utah	Hip Fracture\|Myocardial Ischemia\|Inflammation	September 2014	Phase 2
NCT00418834	Organon and Co	Hypercholesterolemia	January 2007	Phase 3
NCT00654537	AstraZeneca	Hypercholesterolemia	April 2001	Phase 3
NCT02518516	Canadian Network for Observational Drug Effect Studies, CNODES\|Drug Safety and Effectiveness Network, Canada\|Canadian Institutes of Health Research (CIHR)	Hypercholesterolemia	January 2011
NCT05072054	Postgraduate Institute of Medical Education and Research\|Indian Council of Medical Research	Heart Failure With Reduced Ejection Fraction	October 16, 2019	Phase 4
NCT02977065	Chong Kun Dang Pharmaceutical	Dyslipidemias	March 23, 2017	Phase 2
NCT01709513	Regeneron Pharmaceuticals\|Sanofi	Hypercholesterolemia	September 30, 2012	Phase 3
NCT01645410	Dr. Reddy´s Laboratories Limited	Healthy	March 2009	Phase 1
NCT00279708	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Sarcoidosis, Pulmonary	January 2006	Phase 2
NCT00132717	Organon and Co	Hypercholesterolemia	January 1, 2005	Phase 3
NCT00329069	University of Ulm\|Pfizer	Coronary Artery Disease\|Hypercholesterolemia\|Monocyte Function	May 2002	Not Applicable
NCT00974740	Profil Institut für Stoffwechselforschung GmbH\|Pfizer	Type 1 Diabetes	March 2004	Phase 1
NCT00319449	Organon and Co\|PT. Schering-Plough. Tbk Indonesia	Hypercholesterolemia\|Coronary Arteriosclerosis	September 2005	Phase 4
NCT01660191	University of Kansas Medical Center\|Kowa Pharmaceuticals America, Inc.\|Eli Lilly and Company	Hypercholesterolemia	December 2011	Phase 4
NCT00497016	Radboud University Medical Center\|ZonMw: The Netherlands Organisation for Health Research and Development	Hypertension	May 2007	Not Applicable
NCT02842359	Sanofi	Type 2 Diabetes Mellitus	August 23, 2016	Phase 4
NCT01263938	University of Pennsylvania\|National Institute of Allergy and Infectious Diseases (NIAID)	HIV Dementia	September 2011	Phase 4
NCT00814255	NYU Langone Health\|University of Michigan\|The Cleveland Clinic\|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Focal Segmental Glomerulosclerosis	December 2008	Phase 2
NCT00211939	Nabi Biopharmaceuticals	Calcinosis\|Arteriosclerosis\|Hyperparathyroidism, Secondary	January 2005	Phase 4
NCT01370590	Organon and Co	Hypercholesterolemia	September 2011	Phase 3
NCT04952350	Mansoura University	Covid19\|SARS-CoV2 Infection\|COVID-19 Pneumonia	August 14, 2021	Phase 3
NCT00474240	Aegerion Pharmaceuticals, Inc.	Hypercholesterolemia	April 2007	Phase 2
NCT00159718	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Angina	July 2001	Phase 4
NCT02942602	Yonsei University	Hyperlipidemia	April 3, 2014	Not Applicable
NCT03018444	University Hospital, Gentofte, Copenhagen	Diabetes Mellitus, Type 2\|Hydroxymethylglutaryl-CoA Reductase Inhibitors	October 2016	Not Applicable
NCT03338426	Boryung Pharmaceutical Co., Ltd	Essential Hypertension, Dyslipidemia	January 15, 2018	Phase 3
NCT00411190	GlaxoSmithKline	Osteoarthritis	October 19, 2006	Phase 1
NCT03009097	Kamineni Institute of Dental Sciences	Chronic Periaortitis\|Intrabony Periodontal Defect	April 2013	Phase 4
NCT00728910	University of Pennsylvania\|Abbott	Dyslipidemia	June 2008	Phase 2
NCT00770575	Takeda	Cardiovascular Diseases	June 2005	Phase 2
NCT04972396	Altimmune, Inc.	NASH - Nonalcoholic Steatohepatitis	October 5, 2021	Phase 1
NCT02133534	Duke University	Chronic Kidney Disease\|High Cholesterol	February 2008	Phase 4
NCT00639158	Abbott	Dyslipidemias\|Coronary Heart Disease\|Combined (Atherogenic) Dyslipidemia\|Mixed Dyslipidemia	February 2008	Phase 3
NCT05586750	Monash University\|National Health and Medical Research Council, Australia	Dementia, Mixed\|Dementia, Vascular\|Dementia of Alzheimer Type\|Cognitive Decline\|White Matter Hyperintensity\|Aging\|Neuro-Degenerative Disease	September 19, 2019	Phase 4
NCT04943783	Beijing Neurosurgical Institute	Dissecting Aneurysm of Cerebral Artery\|Intramural Hematomas\|Inflammation Vascular	July 1, 2021	Not Applicable
NCT02791958	Ferrer Internacional S.A.	Hypertension	March 2016	Phase 2
NCT04607447	Huashan Hospital	Chronic Subdural Hematoma	August 4, 2020	Not Applicable
NCT02397590	Boryung Pharmaceutical Co., Ltd\|Seoul National University Hospital	Hypertension	March 2015	Phase 1
NCT01674686	Samsung Medical Center	Variant Angina	August 1, 2012	Phase 4
NCT00754507	Daiichi Sankyo, Inc.	Hypercholesterolemia	November 2002	Phase 4
NCT04149483	Beijing Neurosurgical Institute	Intracranial Aneurysm\|Inflammation Vascular	November 7, 2019	Phase 2
NCT00615823	Chinese Academy of Medical Sciences, Fuwai Hospital\|National Grant from The Ministry of Science and Technology\|Capital Development Scientific Fund	Hypertension, Pulmonary	February 2007	Phase 2
NCT02790528	Seung-Jung Park\|CardioVascular Research Foundation, Korea\|Asan Medical Center	Angina Pectoris, Variant\|Statins, HMG-CoA	July 2017	Phase 4
NCT00585611	University of Wisconsin, Madison	Diastolic Heart Failure	December 2005	Not Applicable
NCT02587416	NeuroBo Pharmaceuticals Inc.	Hypercholesteremia	November 2002	Phase 1
NCT05792540	Tanta University\|Eman Ibrahim Elberri, Faculty of Pharmacy, Tanta University\|Fedaa Abd El-monem Kamal El-deen Kotkata Faculty of Pharmacy, Tanta University\|Manal Ali Mahrous Hamouda Faculty of Pharmacy, Menufia University	Depressive Disorder	June 6, 2023	Phase 2
NCT02590653	Penza State University	Myocardial Infarction	October 2014	Phase 4
NCT00979940	Indiana University School of Medicine\|National Center for Research Resources (NCRR)\|Indiana University	Coronary Artery Disease	November 2008	Not Applicable
NCT01646307	Beijing Anzhen Hospital	Focus of Study	January 2012	Phase 4
NCT00504829	Veloxis Pharmaceuticals	Dyslipidemia	July 2007	Phase 2
NCT02254824	Chinese Academy of Medical Sciences, Fuwai Hospital\|Peking University First Hospital\|Peking Union Medical College Hospital\|Beijing Hospital of Traditional Chinese Medicine	Hypertension	October 2013	Phase 4
NCT01527045	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Aggressive Non-Hodgkin Lymphoma\|Blasts Under 5 Percent of Bone Marrow Nucleated Cells\|Chronic Lymphocytic Leukemia\|Loss of Chromosome 17p\|Myelodysplastic+Myeloproliferative Neoplasm\|Non-Hodgkin Lymphoma\|Prolymphocytic Leukemia\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Aggressive Adult Non-Hodgkin Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Chronic Lymphocytic Leukemia\|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Recurrent Diffuse Large B-Cell Lymphoma\|Recurrent Hodgkin Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Non-Hodgkin Lymphoma\|Recurrent Plasma Cell Myeloma\|Recurrent Small Lymphocytic Lymphoma\|Waldenstrom Macroglobulinemia	September 25, 2012	Phase 2
NCT00973986	Liuhuaqiao Hospital\|Guangdong Province, Department of Science and Technology	Coronary Heart Disease	June 2009	Phase 1
NCT01059864	Pfizer	Rheumatoid Arthritis	February 2010	Phase 2
NCT05790499	Wuhan Union Hospital, China	Cholesterol Variability\|Trained Immunity	March 20, 2023	Not Applicable
NCT02579356	Samil Pharmaceutical Co., Ltd.	Diseases of the Circulatory System\|Essential Hypertension	May 2014	Phase 1
NCT00864643	Takeda	Hypercholesterolemia	September 2004	Phase 2
NCT00414531	University of Oslo School of Pharmacy	Myotoxicity of Atorvastatin Treatment	May 2005	Phase 4
NCT01516879	Amgen	Hypercholesterolemia	January 5, 2012	Phase 3
NCT00134238	Pfizer	Mixed Hyperlipidemia	November 2003	Phase 3
NCT02458755	Samsung Medical Center\|Don-A Pharmaceutical, Seoul, South Korea	Stroke\|Intracranial Atherosclerosis	February 2012	Phase 4
NCT02171039	Boehringer Ingelheim	Healthy	June 2006	Phase 1
NCT01081548	Yonsei University	Hypercholesterolemia	August 2008	Phase 4
NCT02219191	Chengdu PLA General Hospital	Rheumatoid Arthritis	August 2014	Not Applicable
NCT03966859	University of Oxford\|Wellcome Trust	Healthy	June 19, 2019	Not Applicable
NCT01527097	shmuel fuchs\|Rabin Medical Center	Psoriasis	August 2012	Phase 3
NCT00491751	Boston University	Peripheral Arterial Disease	May 2004	Phase 1
NCT00529191	Children´s Hospital of Philadelphia\|FDA Office of Orphan Products Development\|Medical University of South Carolina	Type 1 Diabetes	July 2007	Phase 2
NCT05488067	Children´s Hospital of Fudan University	Alagille Syndrome\|Atorvastatin\|Xanthoma	March 22, 2022	Phase 4
NCT00654173	AstraZeneca	Hypercholesterolemia	June 2002	Phase 3
NCT00174330	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Hypertension\|Hyperlipidemia	May 2005	Phase 4
NCT04974814	Beni-Suef University	ST Elevation Myocardial Infarction	May 26, 2021	Not Applicable
NCT00871351	Organon and Co	Primary Hypercholesterolemia	February 1, 2009	Phase 4
NCT01645384	Dr. Reddy´s Laboratories Limited	Healthy	May 2009	Phase 1
NCT03784703	Damanhour University\|Tanta University	Dyslipidemia Associated With Type II Diabetes Mellitus	January 1, 2018	Phase 4
NCT04388501	Janssen Pharmaceutica N.V., Belgium	Healthy	June 7, 2021	Phase 1
NCT01278459	University of Oxford	Pre-Eclampsia	October 2011	Phase 3
NCT02674204	Cedars-Sinai Medical Center\|California Breast Cancer Research Program	Breast Cancer\|Heart Disease\|Cardiotoxicity\|Myocardial Dysfunction	May 5, 2016	Phase 2
NCT02225834	University of Palermo	Ischemic Stroke	November 2011	Phase 4
NCT03066466	Loyola University	Acute Myeloid Leukemia\|Acute Lymphocytic Leukemia\|Myelodysplastic Syndrome	December 10, 2019	Phase 3
NCT05747768	Peking University Third Hospital	Chronic Kidney Disease	July 15, 2022	Phase 4
NCT01842230	Chong Kun Dang Pharmaceutical	Essential Hypertension\|Hyperlipidemia	April 2013	Phase 1
NCT00092716	Organon and Co	Hypercholesterolemia	May 2002	Phase 3
NCT00166504	Organon and Co	Hypercholesterolemia	October 2005	Phase 4
NCT04575857	University of Washington\|Manmohan Cardiothoracic Vascular and Transplant Center\|National Heart, Lung, and Blood Institute (NHLBI)	Rheumatic Heart Disease\|Valvular Disease	February 8, 2022
NCT00296374	AstraZeneca	Diabetes Mellitus	February 2006	Phase 2
NCT00620204	Samsung Medical Center	Angina Pectoris, Variant	January 2008	Phase 4
NCT03079115	Beijing Hospital	Carotid Artery Stenosis	August 21, 2017	Phase 4
NCT00653744	AstraZeneca	Hypercholesterolemia\|Dyslipidaemia	March 2002	Phase 3
NCT03308578	Mayo Clinic\|National Heart, Lung, and Blood Institute (NHLBI)	Sleep Apnea, Obstructive	January 8, 2018	Phase 1\|Phase 2
NCT00653965	AstraZeneca	Hypercholesterolemia\|Dyslipidaemia	May 2003	Phase 3
NCT00289900	Merck Sharp & Dohme LLC	Mixed Hyperlipidemia	January 24, 2006	Phase 3
NCT00479388	Merck Sharp & Dohme LLC	Primary Hypercholesterolemia\|Mixed Dyslipidemia	July 2007	Phase 3
NCT01304641	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Cardiovascular\|Dyslipidemia	November 2009
NCT00678184	Regional Hospital Holstebro	Healthy Subjects	January 2007	Phase 4
NCT02432040	Philippine Dermatological Society	Psoriasis	February 2013	Phase 2
NCT00395486	AstraZeneca	Metabolic Syndrome X	September 2006	Phase 4
NCT00579098	Mayo Clinic\|Pfizer	Atrial Fibrillation\|Arrhythmia\|Inflammation\|Endothelial Dysfunction	December 2007	Phase 4
NCT00977288	Merck Sharp & Dohme LLC	Dyslipidemia	September 2009	Phase 2
NCT04325009	Dong-A ST Co., Ltd.	Healthy	March 30, 2020	Phase 1
NCT03110848	University of Pisa	Thyroid Associated Ophthalmopathy\|Hypercholesterolemia	June 1, 2020	Phase 2
NCT00816244	Lund University Hospital	Breast Cancer\|Postmenopausal	January 2009	Phase 2
NCT05796973	Tampere University Hospital\|Tampere University\|Aalto University\|University of Helsinki\|University of Turku	Prostate Cancer\|Breast Cancer\|Kidney Cancer\|Ovarian Cancer\|Metastatic Breast Cancer\|Metastatic Kidney Cancer\|Metastatic Renal Cell Carcinoma\|Metastatic Renal Cancer\|Metastatic Prostate Cancer\|Metastatic Prostate Adenocarcinoma\|Metastatic Ovarian Cancer\|Metastatic Ovary Cancer	March 31, 2023	Phase 3
NCT05567068	Tanta University	Inflammatory Bowel Diseases	February 1, 2023	Phase 2
NCT01970215	Xention Ltd	Dyslipidemia	August 2013	Phase 2
NCT00640549	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Hyperlipidemia\|Diabetes Mellitus, Type 2\|Non-Insulin Dependent Diabetes Mellitus	March 2003	Phase 4
NCT03195153	University of Roma La Sapienza	Diabetes Mellitus Type 2 Platelets Reactivity Statin	March 28, 2017	Phase 4
NCT02614352	Ahn-Gook Pharmaceuticals Co.,Ltd	Healthy Male Subjects		Phase 1
NCT04221321	HK inno.N Corporation	Healthy	January 7, 2020	Phase 1
NCT00317967	University of Calgary\|Heart and Stroke Foundation of Canada	Hypertrophic Cardiomyopathy	April 2007	Phase 3
NCT01259284	M.D. Anderson Cancer Center	Advanced Cancers	January 2011	Phase 2\|Phase 3
NCT00610870	Samsung Medical Center	Angioplasty, Transluminal, Percutaneous Coronary	July 2007	Not Applicable
NCT01299194	University of Edinburgh\|NHS Lothian	BRONCHIECTASIS	November 2010	Phase 4
NCT03358017	Mario Negri Institute for Pharmacological Research\|Associazione Italiana per la Ricerca sul Cancro	Triple Negative Breast Cancer	March 5, 2018	Phase 2
NCT01856374	Yonsei University	Multi-vessel Diseases, Angina	August 2011	Phase 4
NCT01332747	Jamia Hamdard University	Hyperlipidemia	May 2010	Phase 2
NCT04215237	First Affiliated Hospital Xi´an Jiaotong University	Atherosclerotic Cardiovascular Disease	November 13, 2017	Not Applicable
NCT00664846	Peking Union Medical College Hospital	Stroke	April 2008	Not Applicable
NCT00728988	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Acute Coronary Syndrome	September 2008	Phase 4
NCT01491958	Ohio State University Comprehensive Cancer Center	Acute Myelogenous Leukemia\|Acute Lymphocytic Leukemia\|Myelodysplastic Syndrome	December 10, 2011	Phase 2
NCT01334671	General Hospital of Chinese Armed Police Forces	ST-elevation Myocardial Infarction\|(STEMI)	February 2011	Phase 3
NCT01279590	Furiex Pharmaceuticals, Inc	Myalgia\|Hypercholesterolemia\|Hyperlipidemia	March 2011	Phase 2
NCT00159835	Pfizer	Cardiovascular Diseases	February 1999	Phase 4
NCT01499758	Ranbaxy Laboratories Limited\|Ranbaxy Inc.	Healthy	October 2009	Phase 1
NCT03415178	Sanofi\|Regeneron Pharmaceuticals	Hypercholesterolaemia	March 29, 2018	Phase 3
NCT03604471	Université Catholique de Louvain\|Cliniques universitaires Saint-Luc- Université Catholique de Louvain	Hypercholesterolemia	August 8, 2017	Phase 4
NCT02081638	National Institute of Allergy and Infectious Diseases (NIAID)\|National Institutes of Health Clinical Center (CC)	Human Immunodeficiency Virus	April 18, 2014	Phase 2
NCT00375518	Memorial Sloan Kettering Cancer Center	Thoracic Surgery	July 2006	Not Applicable
NCT02378441	HK inno.N Corporation	Healthy	February 2015	Phase 1
NCT00164086	Bayside Health	Myeloma		Phase 1
NCT01544309	Listen Trial Group	Hypercholesterolemia With Concomitant Type 2 Diabetes	March 2012	Not Applicable
NCT01288469	Sanofi\|Regeneron Pharmaceuticals	Hypercholesterolemia	January 2011	Phase 2
NCT03625089	Chinese University of Hong Kong	Arthritis, Rheumatoid\|Arthritis, Psoriatic	September 1, 2018	Not Applicable
NCT00522158	Baskent University	Type 2 Diabetes Mellitus\|Cardiovascular Disease\|LDL Cholesterol\|Cognition		Phase 4
NCT00654095	Organon and Co	Hypercholesterolemia	December 1, 2007	Phase 3
NCT00115830	Brigham and Women´s Hospital	Atherosclerosis	December 2004	Phase 3
NCT03311841	Merck Sharp & Dohme LLC	Renal Insufficiency	March 1, 2018	Phase 1
NCT00917579	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Hypercholesterolemia	July 2008	Phase 4
NCT00380939	Pfizer	Coronary Arteriosclerosis	April 1999	Phase 4
NCT00650689	Organon and Co\|Merck Sharp & Dohme LLC	Hypercholesterolemia\|Atherosclerosis\|Coronary Artery Disease	May 2003	Phase 3
NCT00435045	GlaxoSmithKline	Hypertriglyceridemia	February 2007	Phase 3
NCT01222182	Mayo Clinic	Hypercholesterolemia	September 2009
NCT00627575	GlaxoSmithKline	Epilepsy	February 4, 2008	Phase 1
NCT02035215	Kuhnil Pharmaceutical Co., Ltd.	Hyperlipidemia, Familial Combined	January 2014	Phase 3
NCT00172419	National Taiwan University Hospital\|National Science Council, Taiwan\|Pfizer	Hyperlipidemia	March 2007	Not Applicable
NCT00653796	Organon and Co\|Merck Sharp & Dohme LLC	Hypercholesterolemia\|Atherosclerosis	September 1, 2003	Phase 4
NCT02411903	The Third Affiliated Hospital of Guangzhou Medical University	Cerebral Infarction\|Clopidogrel,Poor Metabolism of (Disorder)	March 2015	Phase 4
NCT02029573	King Fahad Medical City	Glioblastoma Multiforme	January 1, 2014	Phase 2
NCT00300430	Abbott	Dyslipidemia\|Coronary Heart Disease\|Mixed Dyslipidemia	September 2006	Phase 3
NCT00163150	Pfizer´s Upjohn has merged with Mylan to form Viatris Inc.\|Pfizer	Cerebrovascular Accident\|Hypercholesterolemia	June 2003	Phase 4
NCT02947620	Daewoong Pharmaceutical Co. LTD.	Type II Diabetes\|Dyslipidemia	August 2015	Phase 3
NCT00520585	Masaryk University	Heterogeneity of Cardiomyocytes Repolarisation\|Autonomic Changes of Cardiomyocytes Repolarisation	August 2007	Not Applicable
NCT02715726	Sanofi\|Regeneron Pharmaceuticals	Hypercholesterolemia	July 27, 2016	Phase 3
NCT00700037	Wakayama Medical University	Acute Coronary Syndrome\|Atherosclerosis\|Dyslipidemia	August 2009	Phase 4
NCT02476006	Sanofi\|Regeneron Pharmaceuticals	Hypercholesterolemia	June 23, 2015	Phase 3
NCT00166530	Organon and Co	Atherosclerosis	November 2005	Phase 4
NCT01925937	Isfahan University of Medical Sciences	Congestive Heart Failure	June 2013	Not Applicable
NCT03510884	Sanofi\|Regeneron Pharmaceuticals	Hypercholesterolaemia	May 31, 2018	Phase 3
NCT00090168	Organon and Co	Hypercholesterolemia\|Atherosclerotic Disease\|Coronary Disease	January 27, 2004	Phase 3
NCT00768638	Laval University	Chronic Kidney Disease	October 2008	Phase 4
NCT02370784	Robyn T. Domsic, MD, MPH\|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)\|University of Pittsburgh	Scleroderma	February 2015	Phase 2
NCT00637481	National Cancer Institute (NCI)	Atypical Ductal Breast Hyperplasia\|Breast Cancer\|Ductal Breast Carcinoma in Situ\|Lobular Breast Carcinoma in Situ	March 2008	Phase 1
NCT04047940	Eli Lilly and Company	Healthy	November 29, 2019	Phase 1
NCT04466241	ANRS, Emerging Infectious Diseases\|University of Bordeaux\|PACCI Program	COVID-19\|COVID-19 Drug Treatment\|Severe Acute Respiratory Syndrome Coronavirus 2	November 27, 2020	Phase 2\|Phase 3
NCT02205775	G. d´Annunzio University\|Working Group Aterosclerosi, Trombosi e Biologia Vascolare	Stable Coronary Artery Disease Undergoing PCI	May 2010	Phase 3
NCT03709355	Viriom	HIV-1-infection	November 14, 2018	Phase 1
NCT00664469	Sunnybrook Health Sciences Centre\|Merck Frosst Canada Ltd.\|Schering-Plough	Hypercholesterolemia	August 2007	Phase 3
NCT03611010	Cumberland Pharmaceuticals	Hypercholesterolemia\|Dyslipidemias	August 7, 2018	Phase 2
NCT03024684	Chiayi Christian Hospital\|E-DA Hospital\|National Taiwan University Hospital\|Taichung Veterans General Hospital\|Mackay Memorial Hospital\|Tainan Municipal Hospital\|National Cheng-Kung University Hospital\|Chi Mei Medical Hospital	HepatoCellular Carcinoma	January 3, 2017	Phase 4
NCT04270370	Eli Lilly and Company	Healthy	March 16, 2020	Phase 1
NCT02641899	Intarcia Therapeutics	Healthy	December 2015	Phase 1
NCT01567774	University of Roma La Sapienza	Coronary Artery Disease	April 2012	Phase 4
NCT01785615	University of Rochester\|Pfizer	Metabolic Syndrome	November 2004	Phase 1\|Phase 2
NCT00130481	University of Florida	Type 1 Diabetes Mellitus\|Type 2 Diabetes Mellitus	April 2005	Not Applicable
NCT00356473	University of California, Los Angeles	Rheumatoid Arthritis	March 2003	Phase 4
NCT01370603	Organon and Co	Hypercholesterolemia	September 2011	Phase 3
NCT02584504	Sanofi\|Regeneron Pharmaceuticals	Hypercholesterolemia	November 30, 2015	Phase 3
NCT01692717	Azidus Brasil	Healthy Subjects	February 28, 2013	Phase 1
NCT01112670	University of Colorado, Denver\|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Healthy	November 2009	Phase 4
NCT01544751	Prof Antonino Belfiore\|University Magna Graecia	Nonalcoholic Fatty Liver Disease (NAFLD)	September 2011	Not Applicable
NCT00147602	Pfizer	Cardiovascular Disease	November 1998	Phase 4
NCT00442897	Organon and Co	Hypercholesterolemia	September 2006	Phase 4
NCT02029534	Creighton University	Cardiothoracic Surgery\|Post-operative Atrial Fibrillation	August 2013	Phase 4
NCT02155530	Yonsei University	Coronary Artery Disease	June 2014	Not Applicable
NCT00703261	Merck Sharp & Dohme LLC	Atherosclerotic Vascular Disease	August 2008	Phase 1
NCT02227784	Eli Lilly and Company	Hyperlipidemia	October 2014	Phase 3
NCT02588235	Xijing Hospital	Coronary Artery Disease	October 2015	Phase 4
NCT01605344	UNC Lineberger Comprehensive Cancer Center	Advanced Adenocarcinoma of the Colon or Rectum	April 2012	Phase 1
NCT05327595	Eli Lilly and Company	Diabetes Mellitus, Type 2	May 9, 2022	Phase 1

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL ( 89.50 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.7901 mL	8.9503 mL	17.9006 mL
5 mM	0.3580 mL	1.7901 mL	3.5801 mL
10 mM	0.1790 mL	0.8950 mL	1.7901 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% Saline

Solubility: ≥ 2.5 mg/mL (4.48 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% Corn Oil

Solubility: ≥ 2.5 mg/mL (4.48 mM); Clear solution

* All of the co-solvents are available by MedChemExpress (MCE).