[CAS NO. ] hFSH-β-(33-53) (TFA)

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PRODUCTS SPECIFICATIONS

Catalog

HY-P3343A

Brand

MCE

CAS

-

DESCRIPTION

Overview

MDL	-
Molecular Weight	2657.96
Molecular Formula	C₁₁₇H₁₈₄F₃N₃₁O₃₄S
SMILES	-

For research use only. We do not sell to patients.

Summary

hFSH-β-(33-53) TFA, a thiol-containing peptide which corresponds to a second FSH receptor-binding domain, is a FSHR (follicle-stimulating hormone receptor) antagonist. hFSH-β-(33-53) TFA inhibits binding of FSH to receptor and is a partial agonist of estradiol synthesis in Sertoli cells ^[1] ^[2] ^[3] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 37.62 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.3762 mL	1.8811 mL	3.7623 mL
5 mM	0.0752 mL	0.3762 mL	0.7525 mL
10 mM	0.0376 mL	0.1881 mL	0.3762 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (0.94 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (0.94 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (0.94 mM); Clear solution

* All of the co-solvents are available by MCE.