[CAS NO. 686301-48-4] NB001

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PRODUCTS SPECIFICATIONS [686301-48-4]

Catalog

HY-14425

Brand

MCE

CAS

686301-48-4

For research use only. We do not sell to patients.

NB001 (HTS 09836) is an adenylcyclase 1 (AC1) inhibitor which has effect on neural and non-neural pain by modulating AC1 activity ^[1] .

AC1 ^[1]

NCT Number	Sponsor	Condition	Start Date	Phase
NCT00453401	NanoBio Corporation	Herpes Labialis	February 2007	Phase 2
NCT05290493	Nobias Therapeutics, Inc.	22q11 Deletion Syndrome	February 10, 2022	Phase 2
NCT01324466	NanoBio Corporation	Recurrent Herpes Labialis	April 2011	Phase 3
NCT01695187	NanoBio Corporation	Herpes Labialis	October 2012	Phase 3
NCT01321359	NanoBio Corporation	Recurrent Herpes Simplex Labialis	April 2011	Phase 3

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 50 mg/mL ( 189.16 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% Saline

Solubility: ≥ 1.25 mg/mL (4.73 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in Saline)

Solubility: ≥ 1.25 mg/mL (4.73 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% Corn Oil

Solubility: ≥ 1.25 mg/mL (4.73 mM); Clear solution

* All of the co-solvents are available by MedChemExpress (MCE).