Antitumor agent-85
PRODUCTS SPECIFICATIONS
DESCRIPTION
Overview
| MDL | - |
|---|---|
| Molecular Weight | 419.57 |
| Molecular Formula | C24H33N7 |
| SMILES | CCN(CCCNC1=NC(NC2=NC3=C4CCCC4=CC=C3C(C)=N2)=NC(C)=C1)CC |
Summary
Antitumor agent-85 is a G-quadruplex (G4)-ligand with the ability to stabilize different G4-DNA structures. Antitumor agent-85 has highly effective anti-tumor properties [1] .
In Vitro
Antitumor agent-85 (compound 22a) stabilizes the c-MYC Pu24T, c-MYC Pu22, CKit1, CKit2, KRAS and G4 DNA structures
[1]
.
Antitumor agent-85 (1-10000 nM) inhibits tumor organoids and cancer activated fibroblast (CAF) cells with IC
50
values of 193 and 2816 nM, respectively
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.