[CAS NO. ] EthD-III

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PRODUCTS SPECIFICATIONS

Catalog

HY-D1723

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MCE

CAS

DESCRIPTION

Overview

MDL	-
Molecular Weight	978.36
Molecular Formula	C51H62Cl5N9
SMILES	C[NH+](CCC[NH2+]CCC[N+]1=C(C2=CC(N)=CC=C2C3=C1C=C(C=C3)N)C4=CC=CC=C4)CCC[NH2+]CCC[N+]5=C(C6=CC(N)=CC=C6C7=C5C=C(C=C7)N)C8=CC=CC=C8

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Summary

EthD-III is a nucleic acid probe. EthD-III is a red fluorescent stain that can be used to detect dead cells. EthD-III enters cells with damaged membranes and binds to nucleic acids, resulting in bright red fluorescence in dead cells (Ex/Em=530/645 nm) ^[1] ^[2] .

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References

[1] Anastassov I, et al. Cytoprotection by endogenous zinc in the vertebrate retina. J Neurochem. 2014 Apr;129(2):249-55.
[2] Horie T, et al. OmpA-Like Proteins of Porphyromonas gingivalis Mediate Resistance to the Antimicrobial Peptide LL-37. J Pathog. 2018 Dec 27;2018:2068435.