[CAS NO. ] Chlorotoxin TFA

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PRODUCTS SPECIFICATIONS

Catalog

HY-P0173B

Brand

MCE

CAS

-

DESCRIPTION

Overview

MDL	-
Molecular Weight	4109.74
Molecular Formula	C160H250F3N53O49S11
SMILES	-

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE

[1]Pain. 2021 Jun 1;162(6):1882-1896.

Summary

Chlorotoxin TFA is a peptide isolated from the venom of the scorpion Leiurus quinquestriatus , acts as a chloride channel blocker ^[1] . Anti-cancer activity ^[2] .

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase
NCT04214392	City of Hope Medical Center\|National Cancer Institute (NCI)	Recurrent Glioblastoma\|Recurrent Malignant Glioma\|Recurrent WHO Grade II Glioma\|Recurrent WHO Grade III Glioma	February 26, 2020	Phase 1
NCT00379132	TransMolecular	Breast Cancer\|Non-Small Cell Lung Cancer\|Melanoma\|Colorectal Cancer\|Pancreatic Cancer\|Prostate Adenocarcinoma\|Glioma\|Primary Solid Tumors	August 2006	Phase 1

Appearance

Solid

Source

the venom of the scorpion Leiurus quinquestriatus

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H ₂ O : 12.5 mg/mL ( 3.04 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.2433 mL	1.2166 mL	2.4332 mL
5 mM	---	---	---
10 mM	---	---	---

* Please refer to the solubility information to select the appropriate solvent.