[CAS NO. ] Rabies Virus Glycoprotein TFA

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PRODUCTS SPECIFICATIONS

Catalog

HY-P0285A

Brand

MCE

CAS

-

DESCRIPTION

Overview

MDL	-
Molecular Weight	3380.72
Molecular Formula	C143H218N43F3O45S
SMILES	-

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE

[1]Neurosci Bull. 2021 Mar 29.

Summary

Rabies Virus Glycoprotein (TFA) is a 29-amino-acid cell penetrating peptide derived from a rabies virus glycoprotein that can cross the blood-brain barrier (BBB) and enter brain cells ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H ₂ O : 100 mg/mL ( 29.58 mM ; Need ultrasonic)

DMSO : 100 mg/mL ( 29.58 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.2958 mL	1.4790 mL	2.9579 mL
5 mM	0.0592 mL	0.2958 mL	0.5916 mL
10 mM	0.0296 mL	0.1479 mL	0.2958 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (0.74 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (0.74 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (0.74 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Zou Z, et al. Cre Fused with RVG Peptide Mediates Targeted Genome Editing in Mouse Brain Cells In Vivo. Int J Mol Sci. 2016 Dec 14;17(12).