[CAS NO. ]  Calmodulin-Dependent Protein Kinase II(290-309) acetate

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PRODUCTS SPECIFICATIONS

Catalog
HY-P1479A
Brand
MCE
CAS
-

DESCRIPTION

Overview

MDL-
Molecular Weight2333.88
Molecular FormulaC105H189N31O26S
SMILES-

For research use only. We do not sell to patients.

Summary

Calmodulin-Dependent Protein Kinase II (290-309) acetate is a potent CaMK antagonist with an IC 50 of 52 nM for inhibition of Ca 2+ /calmodulin-dependent protein kinase II [1] .


IC50 & Target

IC50: 52 nM (calmodulin-dependent protein kinase II) [1] .


In Vitro

Peptide 290 to 309 is found to be a potent calmodulin antagonist with an IC 50 of 52 nM for inhibition of Ca 2+ /calmodulin-dependent protein kinase. Neither truncation from the amino terminus (peptide 296-309) nor extension in the carboxyl-terminal direction (peptide 294-319) markedly affects calmodulin binding, whereas shortening the peptide from the carboxyl terminus (peptide 290-302) or from both ends (peptide 295-304) results in the elimination of this activity [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)