Jagged-1 (188-204) (TFA)
PRODUCTS SPECIFICATIONS
DESCRIPTION
Overview
| MDL | - |
|---|---|
| Molecular Weight | 2221.42 |
| Molecular Formula | C95H128F3N25O28S3 |
| SMILES | - |
2 Publications Citing Use of MCE
Summary
In Vitro
Jagged-1 (188-204) is part of the DSL region, and highly conserved between human Jagged-1 and Jagged-2 [2] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Sealed storage, away from moisture
| Powder | -80°C | 2 years |
|---|---|---|
| -20°C | 1 year |
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H 2 O : 50 mg/mL ( 22.51 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 0.4502 mL | 2.2508 mL | 4.5016 mL |
| 5 mM | 0.0900 mL | 0.4502 mL | 0.9003 mL |
| 10 mM | 0.0450 mL | 0.2251 mL | 0.4502 mL |
References
- [1] Jundt F, et al. Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells. Blood. 2004 May 1;103(9):3511-5.
- [2] Weijzen S, et al. The Notch ligand Jagged-1 is able to induce maturation of monocyte-derived human dendriticcells. J Immunol. 2002 Oct 15;169(8):4273-8.
- [3] Nickoloff BJ, et al. Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma. Cell Death Differ. 2002 Aug;9(8):842-55.