ELA-32(human) TFA
PRODUCTS SPECIFICATIONS
DESCRIPTION
Overview
| MDL | - |
|---|---|
| Molecular Weight | 4081.84 |
| Molecular Formula | C172H290F3N63O41S4 |
| SMILES | - |
Summary
ELA-32(human) TFA is a potent, high affinity apelin receptor agonist (IC 50 =0.27 nM; K d =0.51 nM). ELA-32(human) TFA exhibits no binding GPR15 and GPR25. ELA-32(human) TFA activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein translation. ELA-32(human) TFA also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. ELA-32(human) TFA stimulates angiogenesis in HUVEC cells.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Sealed storage, away from moisture and light, under nitrogen
| Powder | -80°C | 2 years |
|---|---|---|
| -20°C | 1 year |
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Solvent & Solubility
H 2 O : 100 mg/mL ( 24.50 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 0.2450 mL | 1.2249 mL | 2.4499 mL |
| 5 mM | 0.0490 mL | 0.2450 mL | 0.4900 mL |
| 10 mM | 0.0245 mL | 0.1225 mL | 0.2450 mL |
-
1.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (24.50 mM); Clear solution; Need ultrasonic