[CAS NO. ] GIP (1-30) amide, porcine TFA

Name: GIP (1-30) amide, porcine TFA
Brand: Arctom Scientific
SKU: HY-P2541A

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PRODUCTS SPECIFICATIONS

Fulfillment

Catalog

HY-P2541A

Brand

MCE

CAS

-

DESCRIPTION

Overview

MDL	-
Molecular Weight	3665.02
Molecular Formula	C164H246F3N41O49S
SMILES	-

For research use only. We do not sell to patients.

Summary

GIP (1-30) amide, porcine TFA is a full glucose-dependent insulinotropic polypeptide (GIP) receptor agonist with high affinity equal to native GIP(1-42) ^[1] . GIP (1-30) amide, porcine is a weak inhibitor of gastric acid secretion and potent stimulator of insulin .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 27.28 mM ; Need ultrasonic)

H ₂ O : < 0.1 mg/mL (ultrasonic) (insoluble)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.2728 mL	1.3642 mL	2.7285 mL
5 mM	0.0546 mL	0.2728 mL	0.5457 mL
10 mM	0.0273 mL	0.1364 mL	0.2728 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: 2.5 mg/mL (0.68 mM); Suspended solution; Need ultrasonic
2.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (0.68 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] L S Hansen, et al. N-terminally and C-terminally truncated forms of glucose-dependent insulinotropic polypeptide are high-affinity competitive antagonists of the human GIP receptor. Br J Pharmacol. 2016 Mar;173(5):826-38.