Caloxin 2A1 TFA
PRODUCTS SPECIFICATIONS
DESCRIPTION
Overview
| MDL | - |
|---|---|
| Molecular Weight | 1592.54 |
| Molecular Formula | C66H92F3N19O24 |
| SMILES | - |
Summary
Caloxin 2A1 TFA is an extracellular plasma membrane Ca 2+ -ATPase (PMCA) peptide inhibitor. Caloxin 2A1 TFA does not affect basal Mg 2+ -ATPase or Na + -K + -ATPase [1] .
In Vitro
Caloxin 2A1 TFA inhibits Ca
2+
-Mg
2+
-ATPase in human erythrocyte leaky ghosts, but it does not affect basal Mg
2+
-ATPase or Na
+
-K
+
-ATPase in the ghosts or Ca
2+
-Mg
2+
-ATPase in the skeletal muscle sarcoplasmic reticulum. Caloxin 2A1 TFA also inhibits Ca
2+
-dependent formation of the 140-kDa acid-stable acylphosphate
[1]
.
Caloxin 2A1 TFA increases airway smooth muscle cells (ASMCs) apoptosis
[2]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Sealed storage, away from moisture
| Powder | -80°C | 2 years |
|---|---|---|
| -20°C | 1 year |
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL ( 62.79 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 0.6279 mL | 3.1396 mL | 6.2793 mL |
| 5 mM | 0.1256 mL | 0.6279 mL | 1.2559 mL |
| 10 mM | 0.0628 mL | 0.3140 mL | 0.6279 mL |
References