[CAS NO. ] SAMβA TFA

Name: SAMβA TFA
Brand: Arctom Scientific
SKU: HY-P3429A

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PRODUCTS SPECIFICATIONS

Fulfillment

Catalog

HY-P3429A

Brand

MCE

CAS

-

DESCRIPTION

Overview

MDL	-
Molecular Weight	1282.24
Molecular Formula	C52H74F3N17O18
SMILES	-

For research use only. We do not sell to patients.

Summary

RNAENFDRF (βIIPKC624-632) TFA is conjugated to the cell permeable peptide TAT47-57, which can be used to form an inhibitory peptide SAMβA. SAMβA, a rationally designed selective antagonist of Mfn1-βIIPKC association. SAMβA is a selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H ₂ O : 50 mg/mL ( 38.99 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.7799 mL	3.8994 mL	7.7989 mL
5 mM	0.1560 mL	0.7799 mL	1.5598 mL
10 mM	0.0780 mL	0.3899 mL	0.7799 mL

* Please refer to the solubility information to select the appropriate solvent.

References

[1] Julio C B Ferreira A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats. Nat Commun. 2019 Jan 18;10(1):329.