[CAS NO. 943962-47-8]  BMS303141

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PRODUCTS SPECIFICATIONS [943962-47-8]

Catalog
SLK-S0277
Brand
Selleck
CAS
943962-47-8

DESCRIPTION [943962-47-8]

Overview

MDLMFCD25976797
Molecular Weight424.30
Molecular FormulaC19H15Cl2NO4S
SMILESO=S(C1=CC(Cl)=CC(Cl)=C1O)(NC2=CC(C3=CC=CC=C3)=CC=C2OC)=O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.3568 mL11.7841 mL23.5682 mL
5 mM0.4714 mL2.3568 mL4.7136 mL
10 mM0.2357 mL1.1784 mL2.3568 mL
50 mM0.0471 mL0.2357 mL0.4714 mL

Description

BMS-303141 is a potent, cell-permeable inhibitor of with IC50 of 0.13 μM. BMS-303141 shows inhibition of total lipid syntheses with IC50 of 8 μM in HepG2 cells.

Targets

ACL [1]
(Cell-free assay)
0.13 μM

In vitro

In HepG2 cells, BMS-303141 shows inhibition of total lipid syntheses with an IC50 of 8 μM, and no cytotoxicity up to 50 lM under a cell based Alamar Blue cytotoxicity assay.