[CAS NO. 745017-94-1] MMAF
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PRODUCTS SPECIFICATIONS [745017-94-1]
Store
Catalog
SLK-S0328
Brand
Selleck
CAS
745017-94-1
DESCRIPTION [745017-94-1]
Overview
| MDL | MFCD25976742 |
|---|---|
| Molecular Weight | 731.96 |
| Molecular Formula | C39H65N5O8 |
| SMILES | O=C(O)[C@@H](NC([C@H](C)[C@H]([C@H]1N(C(C[C@@H](OC)[C@@H](N(C)C([C@@H](NC([C@@H](NC)C(C)C)=O)C(C)C)=O)[C@@H](C)CC)=O)CCC1)OC)=O)CC2=CC=CC=C2 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.3662 mL | 6.8310 mL | 13.6619 mL |
| 5 mM | 0.2732 mL | 1.3662 mL | 2.7324 mL |
| 10 mM | 0.1366 mL | 0.6831 mL | 1.3662 mL |
| 50 mM | 0.0273 mL | 0.1366 mL | 0.2732 mL |
Description
MMAF (Monomethylauristatin F) is a synthetic antineoplastic agent and a potent inhibitor of polymerization. MMAF (Monomethylauristatin F) is applied as a cytotoxic component of antibody-drug conjugates (ADCs) such as vorsetuzumab mafodotin, ABT-414 and SGN-CD19A.
Targets
| Tubulin [1] |
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