[CAS NO. 153168-05-9] Pleconaril

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PRODUCTS SPECIFICATIONS [153168-05-9]

Catalog

SLK-S0436

Brand

Selleck

CAS

153168-05-9

DESCRIPTION [153168-05-9]

Overview

MDL	MFCD00923611
Molecular Weight	381.35
Molecular Formula	C18H18F3N3O3
SMILES	C(F)(F)(F)C1=NC(=NO1)C2=CC(C)=C(OCCCC3=CC(C)=NO3)C(C)=C2

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	2.6223 mL	13.1113 mL	26.2226 mL
5 mM	0.5245 mL	2.6223 mL	5.2445 mL
10 mM	0.2622 mL	1.3111 mL	2.6223 mL
50 mM	0.0524 mL	0.2622 mL	0.5245 mL

Description

Pleconaril (APO-P001, Picovir, VP 63843, WIN 63843) is a inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication with IC50 of < 0.050 μM.

Targets

capsid ^[1]
(Cell-free assay)

0.050 μM

References

[1] K S M Benschop, et al. J Gen Virol. 2015 Mar;96(Pt 3):571-579.

Synonyms

1,2,4-Oxadiazole, 3-[3,5-dimethyl-4-[3-(3-methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoromethyl)-

3-[3,5-Dimethyl-4-[3-(3-methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole

Win 63843

VP 63843

Pleconaril

Picovir