[CAS NO. 486443-73-6] LC3-mHTT-IN-AN1
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PRODUCTS SPECIFICATIONS [486443-73-6]
Catalog
SLK-S0778
Brand
Selleck
CAS
486443-73-6
DESCRIPTION [486443-73-6]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 411.04 |
| Molecular Formula | C15H9Br2NO3 |
| SMILES | O=C1NC2=C(C=C(Br)C=C2)/C1=C/C3=CC(O)=C(O)C(Br)=C3 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.4329 mL | 12.1643 mL | 24.3285 mL |
| 5 mM | 0.4866 mL | 2.4329 mL | 4.8657 mL |
| 10 mM | 0.2433 mL | 1.2164 mL | 2.4329 mL |
| 50 mM | 0.0487 mL | 0.2433 mL | 0.4866 mL |
Description
LC3-mHTT-IN-AN1 is a linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
In vitro
LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured HD mouse neurons.
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