[CAS NO. 56180-94-0] Acarbose

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PRODUCTS SPECIFICATIONS [56180-94-0]

Catalog

SLK-S1271

Brand

Selleck

CAS

56180-94-0

DESCRIPTION [56180-94-0]

Overview

MDL	MFCD00869592
Molecular Weight	645.6
Molecular Formula	C25H43NO18
SMILES	O([C@@H]1[C@@H](CO)O[C@H](O[C@@H]([C@@H]([C@H](C=O)O)O)[C@@H](CO)O)[C@H](O)[C@H]1O)[C@@H]2[C@H](O)[C@@H](O)[C@H](N[C@H]3C=C(CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](C)O2

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	1.5489 mL	7.7447 mL	15.4895 mL
5 mM	0.3098 mL	1.5489 mL	3.0979 mL
10 mM	0.1549 mL	0.7745 mL	1.5489 mL
50 mM	0.0310 mL	0.1549 mL	0.3098 mL

Description

Acarbose(BAY g 5421,Prandase, Precose, Glucobay, Bay-g 5421) is an inhibitor of intestinal , used to treat type 2 diabetes mellitus.

Targets

alpha-glucosidase ^[1]

In vitro

Acarbose reversibly inhibits intestinal alpha-glucosidases, enzymes responsible for the metabolism of complex carbohydrates into absorbable monosaccharide units.

References

[1] Martin AE, et al. Am J Health Syst Pharm, 1996, 53(19), 2277-2290.
[2] Wang PY, et al. Hepatology,?999, 29(1), 161-165.
[3] Okada K, et al. Hepatol Res,?009, 39(5), 490-500.
[4] Russell JC, et al. Metabolism,?993, 42(2), 218-223.
[5] Azuma K, et al. Biochem Biophys Res Commun,?006, 345(2), 688-693.

Synonyms

D-Glucose, O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-

D-Glucose, O-4,6-dideoxy-4-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-, [1S-(1α,4α,5β,6α)]-

O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-D-glucose

BAY-g 5421

Acarbose

Glucobay

Ascarbose

Precose

Prandase

Arcabose

(2R,3R,4R,5R)-4-[[(2R,3R,4R,5S,6R)-5-[[(2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-enyl]amino]tetrahydro-2H-pyran-2-yl]oxy]-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy]-2,3,5,6-tetrahydroxyhexanal

(2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-enyl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal

Acarviostatin I01