[CAS NO. 28395-03-1] Bumetanide

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PRODUCTS SPECIFICATIONS [28395-03-1]

Catalog

SLK-S1287

Brand

Selleck

CAS

28395-03-1

DESCRIPTION [28395-03-1]

Overview

MDL	-
Molecular Weight	364.42
Molecular Formula	C17H20N2O5S
SMILES	O(C1=C(NCCCC)C=C(C(O)=O)C=C1S(N)(=O)=O)C2=CC=CC=C2

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	2.7441 mL	13.7204 mL	27.4409 mL
5 mM	0.5488 mL	2.7441 mL	5.4882 mL
10 mM	0.2744 mL	1.3720 mL	2.7441 mL
50 mM	0.0549 mL	0.2744 mL	0.5488 mL

Description

Bumetanide (Bumex) is a loop diuretic of the sulfamyl category to treat heart failure. Bumetanide is a selective Na+-K+-Cl- cotransporter 1 (NKCC1) inhibitor, weakly inhibits NKCC2, with IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively.

Synonyms

Benzoic acid, 3-(aminosulfonyl)-5-(butylamino)-4-phenoxy-

Benzoic acid, 3-(butylamino)-4-phenoxy-5-sulfamoyl-

3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid

3-n-Butylamino-4-phenoxy-5-sulfamoylbenzoic acid

Bumetanide

3-(Butylamino)-4-phenoxy-5-sulfamoylbenzoic acid

Burinex

Lunetoron

Bufenox

Fordiuran

Bumethanide

PF 1593

Bumex

Lixil

Fontego

Ro 10-6338

Edemex