[CAS NO. 4991-65-5] Tioxolone
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PRODUCTS SPECIFICATIONS [4991-65-5]
Store
Catalog
SLK-S2603
Brand
Selleck
CAS
4991-65-5
DESCRIPTION [4991-65-5]
Overview
| MDL | MFCD00005859 |
|---|---|
| Molecular Weight | 168.17 |
| Molecular Formula | C7H4O3S |
| SMILES | O=C1SC=2C(O1)=CC(O)=CC2 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 5.9464 mL | 29.7318 mL | 59.4636 mL |
| 5 mM | 1.1893 mL | 5.9464 mL | 11.8927 mL |
| 10 mM | 0.5946 mL | 2.9732 mL | 5.9464 mL |
| 50 mM | 0.1189 mL | 0.5946 mL | 1.1893 mL |
Description
Tioxolone(Thioxolone) is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM.
Targets
| CAI [1] |
| 91 nM(Ki) |
In vitro
Tioxolone is reported to possess cytostatic, antipsoriatic, antibacterial and anti-mycotic properties. Tioxolone is also added to some cosmetics (e.g. hair shampoos and skin cleansers), due to claims for its oil-regulating and antibacterial properties. The three-dimensional framework of Tioxolone is further stabilized by π-π interactions between the oxathiolone and benzene rings in partially overlapping molecules.
References
Synonyms
1,3-Benzoxathiol-2-one, 6-hydroxy-
6-Hydroxy-1,3-benzoxathiol-2-one
6-Hydroxy-2-oxo-1,3-benzoxathiole
6-Hydroxy-2-oxobenzoxathiole
Acnosan
Camyna
OL 110
Stepin
Thidoxol
Thioxolon
Tioxolon
Thioxolone
Acnosan (antiseborrheic)
Tioxolone
6-Hydroxybenz[d]oxathiol-2-one
6-(Hydroxy)benzo[d][1,3]oxathiol-2-one
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