[CAS NO. 183204-72-0]  Tipiracil hydrochloride

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PRODUCTS SPECIFICATIONS [183204-72-0]

Catalog
SLK-S3731
Brand
Selleck
CAS
183204-72-0

DESCRIPTION [183204-72-0]

Overview

MDLMFCD01571384
Molecular Weight279.12
Molecular FormulaC9H11ClN4O2.HCl
SMILESC(C1=C(Cl)C(=O)NC(=O)N1)N2C(=N)CCC2.Cl

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM3.5827 mL17.9134 mL35.8269 mL
5 mM0.7165 mL3.5827 mL7.1654 mL
10 mM0.3583 mL1.7913 mL3.5827 mL
50 mM0.0717 mL0.3583 mL0.7165 mL

Description

Tipiracil (MA-1) is an inhibitor of , the enzyme that degrades trifluridine into trifluorothymidine. Its combination with trifluridine increases the bioavailability of trifluridine.

Targets

thymidine phosphorylase [1]


Synonyms

2,4(1H,3H)-Pyrimidinedione, 5-chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-, hydrochloride (1:1)
2,4(1H,3H)-Pyrimidinedione, 5-chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-, monohydrochloride
TPI hydrochloride
TAS 1-462
Tipiracil hydrochloride
5-Chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4(1H,3H)-dione hydrochloride