[CAS NO. 1035072-16-2] ML162
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PRODUCTS SPECIFICATIONS [1035072-16-2]
Catalog
SLK-S4452
Brand
Selleck
CAS
1035072-16-2
DESCRIPTION [1035072-16-2]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 477.40 |
| Molecular Formula | C23H22Cl2N2O3S |
| SMILES | - |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.0947 mL | 10.4734 mL | 20.9468 mL |
| 5 mM | 0.4189 mL | 2.0947 mL | 4.1894 mL |
| 10 mM | 0.2095 mL | 1.0473 mL | 2.0947 mL |
| 50 mM | 0.0419 mL | 0.2095 mL | 0.4189 mL |
Description
ML162 is a covalent inhibitor of cellular phospholipid that induces .
Targets
| GPX-4 [1] |
In vitro
ML-162 increases the expression of p62 and Nrf2 in chemoresistant HN3R and HN3-rslR cells, inactivates Keap1, and increases expression of the phospho-PERK ATF4 SESN2 pathway.
References
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